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[booksz]

Vaccinology Principles and Practice

Vaccinology: Principles and Practice By
2012 | 539 Pages | ISBN: 1405185740 | PDF | 16 MB
Covering all aspects of vaccine research and development in one volume, this authoritative resource takes a comprehensive and systematic approach to the science of vaccinology focusing not only on basic science, but also on the many stages required to commercialize and navigate the regulatory requirements for human application, both in the United States and Europe.Reviews in detail the process of designing a vaccine, from the initial stages of antigen discovery to human applicationIncludes evaluation of vaccine efficacy and safetyDetails clinical trial design, including regulatory requirementsDiscusses the emerging field of active cellular immunotherapyVaccinology: Principles and Practice provides an invaluable resource for clinicians, scientific and medical researchers, lecturers and postdoctoral fellows working in the field of vaccines.Content: Chapter 1 Concept and Scope of Modern Vaccines (pages 1-11): D. Huw Davies, Clint S. Schmidt and Nadeem A. SheikhChapter 2 Strategies to Stimulate Innate Immunity for Designing Effective Vaccine Adjuvants (pages 13-28): Heather L. Wilson, Scott Napper, George K. Mutwiri, Sylvia van Drunen Littel?van den Hurk, Hugh Townsend, Lorne A. Babiuk, Andrew A. Potter and Volker GerdtsChapter 3 Antigen Processing and Presentation by MHC Class I, II, and Nonclassical Molecules (pages 29-46): Antony N. Antoniou, Izabela Lenart, David B. Guiliano and Simon J. PowisChapter 4 Understanding the Mucosal Immune System for Better Mucosal Vaccine Design (pages 47-60): Janine Bilsborough and Joanne L. VineyChapter 5 Immunologic Memory: T Cells in Humans (pages 61-78): Maria Candela Iglesias, Victor Appay and Arnaud MorisChapter 6 Immunologic Memory: B cells (pages 79-93): F. Eun?Hyung Lee and Inaki SanzChapter 7 Utility of Mouse Models in Vaccine Design and Development (pages 94-109): Catharine M. Bosio, Megan MacLeod, Philippa Marrack and Ross M. KedlChapter 8 Utility of Nonhuman Primate Models for Vaccines (pages 110-130): Preston A. Marx and Alexander F. VoevodinChapter 9 Sequence?Based Computational Approaches to Vaccine Discovery and Design (pages 131-149): Darrick CarterChapter 10 Antigen Discovery for Vaccines Using High?Throughput Proteomic Screening Technologies (pages 150-167): D. Huw DaviesChapter 11 Phage Libraries (pages 168-178): Aaron K. SatoChapter 12 Attenuated Bacterial Vaccines (pages 179-195): Richard W. Titball and Helen S. AtkinsChapter 13 Virus?Like Particles as Antigen Scaffolds (pages 196-208): Bryce Chackerian and John T. SchillerChapter 14 Recombinant MVA vaccines: Optimization, Preclinical, and Product Development (pages 209-223): Yper Hall and Miles W. CarrollChapter 15 Recombinant Adenoviruses for Vaccination (pages 224-236): Nelson Cesar Di Paolo, Dmitry Shayakhmetov and Andre LieberChapter 16 Recombinant Avipoxviruses (pages 237-254): Michael A. Skinner and Stephen M. LaidlawChapter 17 Intracellular Facultative Bacterial Vectors for Cancer Immunotherapy (pages 255-274): Patrick Guirnalda, Laurence Wood, Matthew Seavey and Yvonne PatersonChapter 18 Nucleic Acid Vaccination (pages 275-285): Britta Wahren and Margaret A. LiuChapter 19 Artificial Antigen?Presenting Cells: Large Multivalent Immunogens (pages 286-299): Matthew F. Mescher and Julie M. CurtsingerChapter 20 Transcutaneous Immunization via Vaccine Patch Delivery System (pages 301-323): Robert C. Seid and Gregory M. GlennChapter 21 Needle?Free Jet Injection for Vaccine Administration (pages 324-335): Brian R. Sloat, Hoi K. Tran and Zhengrong CuiChapter 22 Oral Vaccines: An Old Need and Some New Possibilities (pages 336-347): Amit A. Lugade, Kalathil Suresh and Yasmin ThanavalaChapter 23 Adjuvants: From Serendipity to Rational Discovery (pages 348-360): Derek T. O'Hagan and Andreas WackChapter 24 Immunostimulatory Properties of Biodegradable Microparticles (pages 361-374): Fiona A. Sharp and Ed C. LavelleChapter 25 Co?Administration of Co?Stimulatory Moieties (pages 375-392): Carolina Arancibia?Carcamo and Yvette LatchmanChapter 26 Toll Receptors in Relation to Adjuvant Effects (pages 393-400): Dipshikha Chakravortty, Amit Lahiri and Priyanka DasChapter 27 Regulatory Issues (FDA and EMA) (pages 401-415): Murrium Ahmad, Victoria Byers and Peter WilsonChapter 28 Immune Monitoring Design within the Developmental Pipeline for an Immunotherapeutic or Preventive Vaccine (pages 417-440): Sylvia Janetzki, Pedro Romero, Mario Roederer, Diane L. Bolton and Camilla JandusChapter 29 Clinical Development Strategy: Nuts and Bolts (pages 441-451): Candida Fratazzi and Claudio CariniChapter 30 Current Approaches to Identify and Evaluate Cancer Biomarkers for Patient Stratification (pages 452-463): Robert Rees, Stephanie Laversin, Cliff Murray and Graham BallChapter 31 Mass Immunization Strategies (pages 465-479): David L. Heymann, R. Bruce Aylward and Rudolf H. TangermannChapter 32 The Role of Mathematical Models in Vaccine Development and Public Health Decision Making (pages 480-508): Marie?Claude Boily, Marc Brisson, Benoit Masse and Roy M. AndersonChapter 33 Vaccine Safety (pages 509-524): John Iskander, Claudia Vellozzi, Jane Gidudu and Robert T. Chen

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[booksz]

Venedig und die Lagune. City Guide ... in die Lagunenstadt eintauchen, Berühmtes u...

Birgit Weichmann, "Venedig und die Lagune. City Guide: ... in die Lagunenstadt eintauchen, Berühmtes und Verstecktes individuell entdecken"
Deutsch | 2010 | pages: 350 | ISBN: 3831718326 | PDF | 12,0 mb

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[booksz]

Violence Against Women and Children, Volume 1 Mapping the Terrain

Dr. Jacquelyn W. White PhD, "Violence Against Women and Children, Volume 1: Mapping the Terrain"
English | ISBN: 1433809125 | 2010 | 332 pages | PDF | 3 MB
This two-part volume provides consensus recommendations for researchers, practitioners, advocates, policymakers, and all those who seek more effective responses to interpersonal violence.

In this volume, top researchers describe prevalence rates among various populations, risk factors for perpetration and vulnerability, and protective factors for potential victims. They also describe the impact of violence on the victims in terms of psychological, reproductive, maternal and child health, and behavioral and economic consequences. In the process, they establish commonalities across academic disciplines and suggest methods for providing better research designs and assessment techniques.

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[booksz]

Violence Against Women and Children, Volume 2 Navigating Solutions

Mary P. Koss, "Violence Against Women and Children, Volume 2: Navigating Solutions"
English | ISBN: 1433809141 | 2010 | 326 pages | PDF | 2 MB
This two-part volume provides consensus recommendations for researchers, practitioners, advocates, policymakers, and all those who seek more effective responses to interpersonal violence.

In this volume, eminent researchers and clinicians use a public health model to examine current societal responses to interpersonal violence. Authors examine the efficacy of medical and psychological treatments for victims, families, and perpetrators, as well as justice system responses to various forms of child abuse, sexual violence, and domestic violence. Interventions are suggested at several levels of prevention, including initiatives designed to eradicate the problem (primary prevention), reduce it among those at risk (secondary prevention), and reduce the negative consequences of violence and stabilize health (tertiary prevention).
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[booksz]

Walk a Mile A Journey Towards Justice and Equity in Canadian Society

Deborah Boutilier, Theresa Anzovino, Jamie Oresar, "Walk a Mile: A Journey Towards Justice and Equity in Canadian Society"
English | 2018 | pages: 350 | ISBN: 0176730273 | PDF | 20,8 mb
Walk a Mile: A Journey Towards Justice and Equity in Canadian Society is the first text of its kind to combine both cognitive and affective dimensions of studying diversity. It does so through an experiential framework that encourages self-reflection on the part of the reader while providing a strong foundation in the history of diversity in Canada. Using as its starting point the notion that creating a more just, inclusive society, requires each of us to figuratively and empathetically walk a mile in the shoes of others, the framework of Walk a Mile facilitates the development of diversity competencies, equipping students to work and live effectively with people from a wide variety of cultural, religious, economic, sexual, and age backgrounds.

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[booksz]

Walking through Darkness A Nature-Based Path to Navigating Suffering and Loss

English | February 13, 2024 | ISBN: 1454950854 | 192 pages | PDF | 7.70 Mb
May the teachings in this book help you walk wakefully as you find your way back home.

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[booksz]

Warriors of Medieval Japan

Warriors of Medieval Japan by Stephen Turnbull
English | September 20, 2011 | ISBN: 1846032202 | 474 pages | MOBI | 34 Mb
Driven by strict codes of honour and bound by deep allegiances of rank, family or religion, the elite warriors of medieval Japan were bold fighters, loyal comrades and deadly enemies.

With rare material from Japanese sources and lavish artwork and photography, this book examines the military lives, beliefs and battle experience of four formidable warrior types - samurai, ninja, warrior monk and ashigaru foot soldier - resulting in a highly authoritative account of Japan's warrior elite.
Warriors of Medieval Japan combines material previously published as Warrior 29: Ashigaru 1467-1649, Warrior 64: Ninja AD 1460-1650, and Warrior 70: Japanese Warrior Monks AD 949-1603, with an added section on Samurai, additional images, and an updated introduction and conclusion.

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We Need To Talk About Xi What we need to know about the world's most powerful leader

We Need To Talk About Xi: What we need to know about the world's most powerful leader by Michael Dillon
English | August 13, 2024 | ISBN: 1529914450 | 208 pages | PDF | 0.98 Mb
A short, urgent book that sorts the fact from the fiction about Xi Jinping - one of the world's most powerful political leaders - to truly understand how he came to power, his hold on China and why we should care.

Meet the most powerful leader in the world.
Chinese premier Xi Jinping graces our television screens and news headlines on a regular basis. But even after a decade in power, he remains shrouded in mystery.
From growing up with a father purged in Mao's Cultural Revolution and his mission to eradicate poverty, to his persecution of Uyghur Muslims and paranoia about being likened to Winnie-the-Pooh, Xi Jinping is a man obscured by caricatures. In this short, essential primer, historian and writer Michael Dillon unveils the character of Xi Jinping - arguably the world's most powerful man - to truly understand his grip on China, what he wants and how the West gets him wrong.
But this is not just the story of Xi; this is the story of today's largest economic powerhouse, which dives into the crux of the issue - what does Xi's leadership of China mean for the rest of the world, and what will he do next?

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[booksz]

White Educators Negotiating Complicity Roadblocks Paved with Good Intentions

Barbara Applebaum, "White Educators Negotiating Complicity: Roadblocks Paved with Good Intentions "
English | ISBN: 1666904155 | 2021 | 156 pages | EPUB | 284 KB
While there is a proliferation of research on white educators who teach courses around anti-racism, White Educators Negotiating Complicity: Roadblocks Paved with Good Intentions focuses on white educators who teach about whiteness to racially diverse groups of students, and who acknowledge and attempt to negotiate their complicity in systemic injustice. Scholars continue to remind white people of the paradox through which their endeavors to disrupt systemic white supremacy often reproduce it. In this book, Barbara Applebaum explores what it means to teach against whiteness while living that paradox.

Rather than an empirical study, this book offers insights from recent scholarship surrounding critical whiteness and epistemic injustice and applies them to some of the most trenchant challenges that white educators face while trying to teach about whiteness to racially diverse groups of students. Introducing the concept of a vigilantly vulnerable and informed humility, Applebaum both illuminates what theory can tell us about praxis and offers guidance for white educators in their attempts to negotiate the effects of white complicity on their pedagogy.
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Why It's OK to Enjoy the Work of Immoral Artists

Why It's OK to Enjoy the Work of Immoral Artists by Mary Beth Willard
English | March 2, 2021 | ISBN: 0367898659, 0367898640 | True EPUB | 192 pages | 0.2 MB
The #metoo movement has forced many fans to consider what they should do when they learn that a beloved artist has acted immorally. One natural thought is that fans ought to give up the artworks of immoral artists. In Why It's OK to Enjoy the Work of Immoral Artists, Mary Beth Willard argues for a more nuanced view. Enjoying art is part of a well-lived life, so we need good reasons to give it up.

And it turns out good reasons are hard to find. Willard shows that it's reasonable to believe that most boycotts of artists won't succeed, so most of the time there's no ethical reason to join in. Someone who manages to separate the art from the artist isn't making an ethical mistake by buying and enjoying their art. She then considers the ethical dimensions of canceling artists and the so-called "cancel culture," arguing that canceling is ethically risky because it encourages moral grandstanding. Willard concludes by arguing that the popular debate has overlooked the power of art to change our lives for the good.
It's of course OK to decide to give up the artwork of immoral artists, but - as Willard shows in this provocative little volume - it's OK to continue to enjoy their art as well.
Key Features
Offers accessible discussions of complicated philosophical topics like aesthetic value, collective action problems, and epistemic justiceProvides a unique perspective and underexplored argument on the popular issue of cancellationExplores the role of aesthetic value in our lives, including its relation to our ethical decisions and our well being

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[booksz]

William Goldfarb, Water Law

William Goldfarb, "Water Law"
English | 1988 | pages: 309 | ISBN: 0873711114 | PDF | 6,9 mb
This revised second edition is essential to everyone involved with water and water resources-complying with the myriad federal, state, and local laws and regulations that govern the use and management of water in our attempts to maintain, clean, usable water. It includes the law of water diversion and distribution; water resources development and protection; water treatment and land use; ocean dumping; oil and hazardous substances cleanup; riparian and non-riparian systems; Eastern permit systems; beneficial use; water codes; prior appropriation; surface and ground water; channel modifications; municipal water supply; irrigation; California Water Management Districts; Bureau of Reclamation; Corps of Engineers; Water Resources Development Act of 1986; SCS, TVA, BPA, NEA, CERCLA, CWA, SDWA, RCRA, and their substantial changes in the last four years; water resources planning and research; public use; ownership of beds and banks; wild and scenic rivers; river corridor and instream flow protection; flood insurance, Section 404 and Section 208; the Supreme Court and water conservation; heat dischargers; quality-based effluent limitations; state ground water programs; pretreatment; funding; enforcement; citizen suits; and many more vital topics.

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[booksz]

Wir Klimakiller - Wie wir die Erde retten können

Tim Flannery, "Wir Klimakiller - Wie wir die Erde retten können"
Deutsch | 2007 | pages: 308 | ISBN: 359685248X, 3596807352 | PDF | 8,6 mb

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[booksz]

Workbook for Diagnostic Medical Sonography Obstetrics and Gynecology (5th Edition)

Workbook for Diagnostic Medical Sonography: Obstetrics and Gynecology
English | 2023 | ISBN: 1975177029 | 609 Pages | EPUB (True) | 63 MB
Designed to accompany the 5th Edition of Susan Raatz Stephenson and Julia Dmitrieva's text, Workbook for Diagnostic Medical Sonography: A Guide to Clinical Practice, Obstetrics and Gynecology, 5th Edition, by Barbara Hall-Terracciano and Susan R. Stephenson, offers a full complement of self-study aids for active learning that enable you to assess and build your knowledge as you advance through the text. Most importantly, it helps you get the most out of your study time, with a variety of custom-designed exercises to help you master each objective.

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Working with Data in the Public Sector From Fear to Enthusiasm

Working with Data in the Public Sector: From Fear to Enthusiasm
English | 2025 | ISBN: 1032803029 | 222 Pages | PDF EPUB (True) | 8.4 MB
Authors Anne McIntyre-Lahner and Ronald Schack explore different types and degrees of data fear (a data fear/data comfort continuum) and provide a toolbox of fear-fighting techniques, including methods of dealing with data fear "in the moment," methods of mitigating data fear related to using, sharing, and reporting data, and demonstrating how many common data tasks need not be scary. They further offer a self-assessment instrument and process to help individuals assess their level of data fear/comfort, identifying which specific dimensions of data fear/comfort may be most problematic at both the individual and organizational level. The book examines how individual data fear can "infect" organizations, collaboratives, and communities and how to "bake in" data fear prevention in one's efforts to create and sustain a data-informed culture.

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Working With Narrative in Emotion-Focused Therapy Changing Stories, Healing Lives

Dr. Lynne Angus PhD, "Working With Narrative in Emotion-Focused Therapy: Changing Stories, Healing Lives"
English | ISBN: 1433809699 | 2011 | 170 pages | PDF | 2 MB
In this book, Lynne E. Angus and Leslie S. Greenberg present a groundbreaking, empirically based model that integrates working with narrative and emotion processes in emotion-focused therapy (EFT).

Individual chapters describe how the interaction between emotion and narrative creates a constantly evolving sense of self; how clinicians can address both narrative and emotion processes to help clients create more adaptive, empowering meanings and sense of self; and the importance of a strong therapeutic alliance. Engaging, in-depth case studies illustrate how the model can be applied to treatment of depression and emotional trauma.

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[booksz]

Working with Network Data

Working with Network Data: A Data Science Perspective
English | 2024 | ISBN: 1009212591 | 554 Pages | PDF | 15 MB
Drawing examples from real-world networks, this essential book traces the methods behind network analysis and explains how network data is first gathered, then processed and interpreted. The text will equip you with a toolbox of diverse methods and data modelling approaches, allowing you to quickly start making your own calculations on a huge variety of networked systems. This book sets you up to succeed, addressing the questions of what you need to know and what to do with it, when beginning to work with network data. The hands-on approach adopted throughout means that beginners quickly become capable practitioners, guided by a wealth of interesting examples that demonstrate key concepts. Exercises using real-world data extend and deepen your understanding, and develop effective working patterns in network calculations and analysis. Suitable for both graduate students and researchers across a range of disciplines, this novel text provides a fast-track to network data expertise.

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[booksz]

Xuxub Must Die The Lost Histories Of A Murder On The Yucatan

Paul Sullivan, "Xuxub Must Die: The Lost Histories Of A Murder On The Yucatan "
English | ISBN: 0822942305 | 2004 | 272 pages | PDF | 5 MB
Today, foreigners travel to the Yucatan for ruins, temples, and pyramids, white sand beaches and clear blue water. One hundred years ago, they went for cheap labor, an abundance of land, and the opportunity to make a fortune exporting cattle, henequen fiber, sugarcane, or rum. Sometimes they found death. In 1875 an American plantation manager named Robert Stephens and a number of his workers were murdered by a band of Maya rebels. To this day, no one knows why. Was it the result of feuding between aristocratic families for greater power and wealth? Was it the foreseeable consequence of years of oppression and abuse of Maya plantation workers? Was a rebel leader seeking money and fame-or perhaps retribution for the loss of the woman he loved? For whites, the events that took place at Xuxub, Stephens's plantation, are virtually unknown, even though they engendered a diplomatic and legal dispute that vexed Mexican-U.S. relations for over six decades. The construction of "official" histories allowed the very name of Xuxub to die, much as the plantation itself was subsumed by the jungle. For the Maya, however, what happened at Xuxub is more than a story they pass down through generations-it is a defining moment in how they see themselves. Sullivan masterfully weaves the intricately tangled threads of this story into a fascinating account of human accomplishments and failings, in which good and evil are never quite what they seem at first, and truth proves to be elusive. Xuxub Must Die seeks not only to fathom a mystery, but also to explore the nature of guilt, blame, and understanding.

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Yoga for Menopause and Beyond Guiding Teachers and Students Through Change

Yoga for Menopause and Beyond: Guiding Teachers and Students Through Change by Niamh Daly
English | June 3, 2024 | ISBN: 1718236913 | 224 pages | MOBI | 24 Mb
In recent years there has been a surge in awareness surrounding the challenges experienced by menopausal women, along with impassioned calls for more specialized support from health and wellness professionals. In Yoga for Menopause and Beyond, author Niamh Daly shares how yoga teachers can help answer these calls.

Written in an open and heartfelt conversational style, this book is a reimagining of yoga viewed through the lens of menopause. It will help you understand which elements of yoga are already ideal, what may be unhelpful, and what you might add to support symptom relief, health, and self-esteem.
Daly addresses topics such asbiochemical, physical, social, and emotional impacts of menopause;specific physiological effects that necessitate a changed approach to asana;changes to the nervous system that influence what practices we choose;changing health risks and how the benefits of yoga can help reduce these risks;using movement for comfort and pleasure through somatics and instinctual movement;reconsidering your language to be inclusive of the broad array of possible experiences, including trauma sensitivity;incorporating what you learn into a class or workshop;empowering women through knowledge and recommendations;research and the importance of transparency in offering yoga tools for menopause; andpractical advice, for within a class and outside, including sections on nutrition and medical options.Yoga for Menopause and Beyond is the ideal guide for anyone wishing to create a relevant and supportive yoga practice for women as they journey through menopause and into the postmenopause years.

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[booksz]

Zodiac Signs Gemini

Zodiac Signs: Gemini by Colin Bedell
English | February 4, 2020 | ISBN: 1454938935 | 128 pages | PDF | 1.02 Mb
A new series of sign-by-sign guides from contemporary astrologers.

Astrology is a vital tool for understanding our place in the world and the universal forces that move us. A cosmic calling rather than a fated destiny, our astrological sign is a key to uncovering our mission here on earth. Learn about how your sign grows from child to adult, fits in at school and at work, and functions best as a friend, lover, parent, and more. In these practical and empowering guides to the zodiac signs, contemporary astrologers teach you to use this dynamic language to better understand yourself and the people around you.

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[booksz]

Zodiac Signs Leo

Zodiac Signs: Leo by Bess Matassa
English | February 4, 2020 | ISBN: 1454938943 | 144 pages | PDF | 1.25 Mb
A new series of sign-by-sign guides from contemporary astrologers.

Astrology is a vital tool for understanding our place in the world and the universal forces that move us. A cosmic calling rather than a fated destiny, our astrological sign is a key to uncovering our mission here on earth. Learn about how your sign grows from child to adult, fits in at school and at work, and functions best as a friend, lover, parent, and more. In these practical and empowering guides to the zodiac signs, contemporary astrologers teach you to use this dynamic language to better understand yourself and the people around you.

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