Tripos SYBYL-X 2.1.1 (Win/Mac/Linux) | 851/616/835 MB
Additionally, the science offered by SYBYL-X provides unique, competitive advantages in a number of areas vital for today's successful discovery research:
3D QSAR: use the power of industry leading CoMFA in a new way to generate novel ideas for R-groups - predict the level of biological activity or potency based on structure-activity data, not just yes/no activity predictions
Ligand-based virtual screening: search millions of compounds overnight - don't miss hits because you only screened subsetted portions of your database
Cheminformatics: produce highly focused queries that avoid false positives using rich set of 3D queries; on-the-fly conformational searching means you only store a single conformation of your molecules, keeping database size small and very transportable
Docking: custom tailor and fine-tune docking to a particular receptor site using information like SAR or known poses to improve rank ordering of ligands.
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