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Dipeptidyl Aminopeptidases: Basic Science and Clinical Applications By Inger Brandt, Anne-Marie Lambeir, Marie-Berthe Maes, Simon Scharpé, Ingrid De Meester (auth.), Uwe Lendeckel, Dirk Reinhold, Ute Bank (eds.)
2006 | 226 Pages | ISBN: 0387290583 | PDF | 4 MB
Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses, and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes. Leading experts in the field will contribute to this book, which will present a state-of-the-art view on these enzymes at a time when our understanding of their function is growing ever more rapidly and therapeutic options have become imminent. The sections of the book will focus on various topics including DP IV and related enzymes in: expression and function, metabolic disorders, immune mechanisms and immune disorders, neuronal diseases and cancer, and related drug development.

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Amar Wahab, "Disciplining Coolies: An Archival Footprint of Trinidad, 1846"
English | 2018 | ISBN: 1433156164 | PDF | pages: 302 | 4.1 mb
The early years of the East Indian Indentureship system in the Caribbean saw experiments on "coolie" laborers under the British Empire. Colonial Trinidad was one of the main sites for this experiment. This book foregrounds one of the earliest cases (1846) of occupational and physical cruelty against East Indian indentured laborers in Trinidad within this very early period of experimentation. It presents and analyzes the full transcripts of an inquiry concerning the ill-treatment of "coolie" laborers and the severe punishment and death of one laborer, Kunduppa, by a Scottish planter in Trinidad. Drawing on the concepts of discipline, governmentality, and Orientalism, the main argument of the manuscript is that within the early experimental period of Indentureship, the figure of the "coolie" and disciplinary tactics of bodily torture were instrumental to redrafting and stabilizing the colonial governance of contract labor. It also argues that Crown investigations of "coolie" abuse and death became occasions for establishing a new colonial order, in which the disciplinary powers of planters were curbed in the interest of protecting and "caring" for the "coolie" ―a discourse that was crucial to re-inventing colonial rule as benevolent. As such, the author's analysis of colonial violence has crucial implications for critically re-thinking colonial liberalism and its legacies in the present.

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Parvati Nair, "Displacement, Environments, and Photo-Politics in the Mediterranean: Migrant Sea "
English | ISBN: 135011619X | 2024 | 178 pages | EPUB, PDF | 6 MB + 10 MB
Focusing on the Mediterranean region from 2015 onwards, this volume explores photography's engagement with displacement, a process that denotes the environmental and social breakdown of places and the forced mobility of people.

The ongoing proliferation of photography of the displaced plays a crucial role in shaping opinions, by sensitising the public to the despair of displacement and hardening them to the trope through repeated exposure. Through a range of images by both established and amateur photographers, as well as ethnographic notes that draw from interviews with actors who are either displaced or working with the displaced, Parvati Nair questions the extent to which photography opens a space of possibility for the displaced in the face of globally dominant ideological drives that lead to the Anthropocene. Chapters focus on key aspects of this mass phenomenon, such as the question of crises no longer as exception but as historical process, the lived experiences of protracted relegation to borders and exposure to possible death, the prevalence of domicide and the spread of encampments, and the question of hope for the future.
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Martin W. Bowman - Douglas (Images of America)
Tempus | 1999 | ISBN: 0752416154 | English | 132 pages | PDF | 104.1 MB
For a general introduction to the Douglas Aircraft Corporation, this book serves its purpose. However, it is just that, an introduction. As with other titles in the Images of America series, this volume relies heavily on photographs and illustration. Therefore, anyone wanting a more in-depth history of the company or a particular aircraft will have to look further.

The book opens with an introduction to Donald Douglas, the founder of the company that bears his name. Chapter 1 covers military types through World War II, including aircraft designed by other companies but built at the Douglas factories, such as the Boeing B-17. Chapter 2 covers airliners and military transports from the DC-1 through the DC-9/C-9, including such limited-edition and one-off aircraft as the DC-1, DC-4E, and DC-5. Though several KLM aircraft are included, I was surprised that KLM's PH-AJU, second-place winner in the England-to-Australia race was not. Chapter 3 returns to the military, covering X-planes and Navy jets, and Chapter 4 covers McDonnell Douglas commercial and military aircraft, including the helicopters built by Hughes. Readers will be disappointed in the lack of coverage of McDonnell Douglas airliners; there is no mention of the MD-90, MD-95/Boeing 717-200 series or the final acquisition of that company by Boeing.

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Drawing Spooky Chibi: Learn How to Draw Kawaii Vampires, Zombies, Ghosts, Skeletons, Monsters, and Other Cute, Creepy, and Gothic Creatures (How to Draw Books) by Sarah E. White, Tessa Creative Art
English | May 23, 2023 | ISBN: 1646044967 | 128 pages | MOBI | 38 Mb
Step-by-step tutorials on how to draw a variety of anime- and manga-style chibi monsters, including vampires, zombies, ghosts, and other cute and scary monsters!

Get your sketchbook ready-it's time to take your drawing skills to the next level with Drawing Spooky Chibi! A comprehensive guide with easy-to-follow instructions and tips and handy practice pages, this latest installment in the Drawing Chibi series will have you oohing and awwing at a number of creepy creatures and malicious monsters, including:Black CatsScary DollsWitches and WizardsKiller ClownsFrankenstein's MonsterCthulhuAnd many more!Whether you're a budding artist or a drawing master, Drawing Spooky Chibi makes drawing your favorite creatures of the night in anime-style fun and easy!

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Stephen Baxter, "Early Medieval Studies in Memory of Patrick Wormald "
English | ISBN: 1138248193 | 2017 | 604 pages | PDF | 40 MB
Patrick Wormald was a brilliant interpreter of the Early Middle Ages, whose teaching, writings and generous friendship inspired a generation of historians and students of politics, law, language, literature and religion to focus their attention upon the world of the Anglo-Saxons and the Franks. Leading British, American and continental scholars - his colleagues, friends and pupils - here bear witness to his seminal influence by presenting a collection of studies devoted to the key themes that dominated his work: kingship; law and society; ethnic, religious, national and linguistic identities; the power of images, pictorial or poetic, in shaping political and religious institutions. Closely mirroring the interests of their honorand, the collection not only underlines Patrick Wormald's enormous contribution to the field of Anglo-Saxon studies, but graphically demonstrates his belief that early medieval England and Anglo-Saxon law could only be understood against a background of research into contemporary developments in the nearby Welsh, Scottish, Irish and Frankish kingdoms. He would have been well pleased, therefore, that this volume should make such significant advances in our understanding of the world of Bede, of the dynasty of King Alfred, and also of the workings of English law between the seventh and the twelfth century. Moreover he would have been particularly delighted at the rich comparisons and contrasts with Celtic societies offered here and with the series of fundamental reassessments of aspects of Carolingian Francia. Above all these studies present fundamental reinterpretations, not only of published written sources and their underlying manuscript evidence, but also of the development of some of the dominant ideas of that era. In both their scope and the quality of the scholarship, the collection stands as a fitting tribute to the work and life of Patrick Wormald and his lasting contribution to early medieval studies.

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Mark R. Royce, "Ecclesiology, Idealism, and World Polity: The Concordats of the Apostolic See "
English | ISBN: 3031570324 | 2024 | 301 pages | EPUB | 1062 KB
This book provides the only comprehensive analysis of concordats, the international treaties of the Apostolic See in Rome. Identifying the 167 treaties between the papacy and civil commonwealths from 1865 to 2022 at the intersection of canon, comparative, and international law, Royce indicates an overall relationship between the dominance or inferiority of Roman Catholic canon law within the contracting party and the respective ecclesiological or ideational norms of its concordat. Successive case chapters analyzing the concordats with fascist Europe, the German Länder, Latin American countries, France and Austria, the states of the Second Vatican Council, and Third World states illustrate that the norms of concordats with polities of long-standing, entrenched, continuous, or otherwise dominant Roman Catholic canon law concern the Church as an institution, whereas those with polities of new, precarious, inconstant, or otherwise inferior canon law status concern the Church as anadherent to values. This contractual law of the Apostolic See most closely aligns with the tenets of the English School of international theory. As a result, this book posits significant theoretical, legal, and empirical advances in existing knowledge of the international relations and law of the Catholic Church.

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United Nations, "Economic Development in Africa: Debt Sustainability Oasis or Mirage"
English | 2004 | pages: 98 | ISBN: 9211126487 | PDF | 6,8 mb
In the context of the Millennium Development Goals (MDGs), the international community has set itself a target of reducing poverty by half by the year 2015. Many observers have now come to the conclusion that, on present trends, there is very little likelihood that this objective can be achieved at any time close to that date in the poorer countries, including in Africa. The continent's debt problems and its resource requirements are inextricably linked to the capacity of African countries to generate capital accumulation and growth. The current study questions Africa's debt sustainability and tries to put these and other related issues in perspective making a number of recommendations on how to deal with Africa's debt overhang, either through the adoption of new approaches or a major revision and improvement of present debt relief policies.

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Emancipation: The Abolition and Aftermath of American Slavery and Russian Serfdom by Peter Kolchin
English | September 10th, 2024 | ISBN: 0300273665 | 568 pages | True EPUB | 1.57 MB
In this sequel to his landmark study, historian Peter Kolchin compares the transition to freedom after American emancipation with the Russian Great Reforms

The two largest transitions from unfree to free labor of the many that occurred in Europe and the Americas during the nineteenth century took place in the United States and in Russia. Both occurred in the 1860s, and in both the former slaves and serfs strove to maximize their autonomy and freedom while the former masters worked to preserve as many of their prerogatives as possible. Both were partially-but only partially-successful.
In this magisterial and long-awaited work, historian Peter Kolchin shows that a more radical break with the past was possible in the United States than in Russia, with the Southern freedpeople coming to enjoy republican citizenship, whereas Russian peasants remained subjects rather than citizens. Both countries saw conservative reactions triumph in the late nineteenth century. While this conservatism was common in most emancipations, it was especially strong in Russia and the American South, in part as a reaction against the major efforts to restructure the social order that went by the name of Reconstruction in the United States and the Great Reforms in Russia.

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Andrea Scarantino, "Emotion Theory: The Routledge Comprehensive Guide: Volume II: Theories of Specific Emotions and Major Theoretical Challe"
English | ISBN: 1032743727 | 2024 | 718 pages | EPUB | 10 MB
Emotion Theory: The Routledge Comprehensive Guide is the first interdisciplinary reference resource which authoritatively takes stock of the progress made both in the philosophy of emotions and in the affective sciences from Ancient Greece to today. A two-volume landmark publication, it provides an overview of emotion theory unrivaled in terms of its comprehensiveness, accessibility and systematicity.

Comprising 62 chapters by 101 leading emotion theorists in philosophy, classics, psychology, biology, psychiatry, neuroscience and sociology, the collection is organized as follows:
Volume I:
Part I: History of Emotion Theory (10 chapters)
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Engineering Applications of Neural Networks: 14th International Conference, EANN 2013, Halkidiki, Greece, September 13-16, 2013 Proceedings, Part I By Anastasios Tefas, Alexandros Iosifidis, Ioannis Pitas (auth.), Lazaros Iliadis, Harris Papadopoulos, Chrisina Jayne (eds.)
2013 | 510 Pages | ISBN: 364241012X | PDF | 17 MB
The two volumes set, CCIS 383 and 384, constitutes the refereed proceedings of the 14th International Conference on Engineering Applications of Neural Networks, EANN 2013, held on Halkidiki, Greece, in September 2013. The 91 revised full papers presented were carefully reviewed and selected from numerous submissions. The papers describe the applications of artificial neural networks and other soft computing approaches to various fields such as pattern recognition-predictors, soft computing applications, medical applications of AI, fuzzy inference, evolutionary algorithms, classification, learning and data mining, control techniques-aspects of AI evolution, image and video analysis, classification, pattern recognition, social media and community based governance, medical applications of AI-bioinformatics and learning.

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Lothar Schäfer, Thomas Schnelle, "Entstehung und Entwicklung einer wissenschaftlichen Tatsache. Einführung in die Lehre vom Denkstil und Denkkollektiv."
Deutsch | 2021 | ISBN: 3518279122 | PDF | pages: 252 | 10.6 mb
Originally published in German in 1935, this monograph anticipated solutions to problems of scientific progress, the truth of scientific fact and the role of error in science now associated with the work of Thomas Kuhn and others. Arguing that every scientific concept and theory-including his own-is culturally conditioned, Fleck was appreciably ahead of his time. And as Kuhn observes in his foreword, "Though much has occurred since its publication, it remains a brilliant and largely unexploited resource.""To many scientists just as to many historians and philosophers of science facts are things that simply are the they are discovered through properly passive observation of natural reality. To such views Fleck replies that facts are invented, not discovered. Moreover, the appearance of scientific facts as discovered things is itself a social construction, a made thing. A work of transparent brilliance, one of the most significant contributions toward a thoroughly sociological account of scientific knowledge."-Steven Shapin, Science

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Epigenetics in Oncology (Cancer Treatment and Research, 190) by Jianjun Chen, G. Greg Wang, Jun Lu
English | December 20, 2023 | ISBN: 303145653X | 399 pages | MOBI | 10 Mb
This book addresses Epigenetics in Cancer and covers the most recent advances in RNA/histone/DNA epigenetics in Oncology. RNA/histone/DNA epigenetics have been shown to play pivotal roles in cancer initiation, progression, maintenance and drug response/resistance, tumor microenvironment, cancer stem cell self-renewal, cancer metabolism, and tumor immune evasion. In particular, research in RNA cancer epigenetics has made impressive progress in the last few years.

Individual chapters in Part I (focusing on RNA epigenetics) are devoted to RNA modifications in Cancer Metabolism and Microenvironment, Cancer Stem Cell Biology, Immune Surveillance, Solid Tumors and Tumor Immunity, and Hematopoietic Malignancies, as well as to RNA editing in Cancer. Chapters in Part II and III of the book focus on histone epigenetics and DNA epigenetics, respectively.
By familiarizing readers with the latest developments in this complex and challenging field, the book offers a valuable resourcefor scientists, graduate students and clinicians alike.

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Michael Huemer, "Epistemology: Contemporary Readings "
English | ISBN: 0415259215 | 2002 | 636 pages | PDF | 5 MB
This comprehensive anthology draws together classic and contemporary readings by leading philosophers on epistemology. Ideal for any philosophy student, it will prove essential reading for epistemology courses, and is designed to complement Robert Audi's textbook Epistemology: A Contemporary Introduction (Routledge, 1998).

Themes covered include, perception, memory, inductive inference, reason and the a priori, the architecture of knowledge, skepticism, the analysis of knowledge, testimony. Each section begins with an introductory essay, guiding students into the topic.
Includes articles by:
Russell, Hume, Berkeley, Malcolm, Quine, Carnap, J.L. Austin, Pollock, Nozick, Putnam, G.E. Moore, Huemer, Reid, Plato, BonJour, Coady, Carroll, Fumerton, Edwards, Foster, Howson, Urbach, Stove, Empiricus, Oakley, Alston, Gettier, Clark, Goldman, Lehrer, Paxson, DeRose, Dretske, Klein and Chisholm
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Erotic Integrity: How to be True to Yourself Sexually by Claudia Six,
English | May 10th, 2016 | ISBN: 1631520792 | 288 pages | True EPUB | 2.80 MB
Have you ever asked yourself the following questions: Are my desires normal? Can I share who I really am with my partner? Am I morally flawed because of my sexual fantasies?

Is there something wrong with me sexually because I have low libido? In Erotic Integrity, Dr. Claudia Six leads readers through ten sexual themes-including garden-variety performance anxiety, sexual boredom, newly dating, coming out, and more-and reveals three simple steps to a more rewarding sex life: knowing who you truly are as a sexual being, embracing that knowledge, and living it authentically.
Frankly presented and illustrated with candid case studies, these steps can be applied by individuals and couples of all ages and sexual orientations, with or without children. Based on Dr. Six's twenty years experience as a clinical sexologist, this straightforward guide skillfully challenges readers to self-examine, self-accept, and self-actualize for a more fulfilling sense of eroticism.

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