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Free Download Schrodinger Suites 2025-1 Linux | 11.1 Gb
The software developerSchrödingercontinuously strive to develop scientific solutions that push the boundaries of molecular design and are delighted to share enhanced drug discovery and materials workflows inSchrödinger's 2025-1software release
Owner:Schrödinger, LLC
Product Name:Schrödinger Suites
Version:2025-1 Commercial Version
Supported Architectures:x64
Website Home Page :[Ссылки доступны только зарегистрированным пользователям . Регистрируйся тут...]
Languages Supported:english
System Requirements:Linux *
Size:11.1 Gb
.


Small Molecule Drug Discovery
Target Validation & Structure Enablement
Protein Preparation
- Improved peptide bond connectivity by better integration of sequence information in the Protein Preparation Workflow (PPW)
Protein X-Ray Refinement
- Phenix/OPLS can now run from CIF files containing reflections
Cryo-EM Model Refinement
- Improved support of macrocycles in GlideEM/GlideXtal
Binding Site & Structure Analysis
Binding Site Characterization
- Rationalize kinase selectivity challenges using the Kinase Conservation Analysis Interface that combines sequence and complex structural information: Identify promising selectivity handle residues to modulate ligand kinase selectivity that can be tested with FEP+ Residue Scan
Desmond Molecular Dynamics
- Optimize the unbinding kinetics of protein-ligand complexes using dissolution rate predictions based on unbinding pathways identified by enhanced sampling methods
Mixed Solvent MD (MxMD)
- Identify potential binding sites and assess drugability of competitive and allosteric binding sites with the full release of a Mixed Solvent Molecular Dynamics Interface to setup and analyze MxMD simulations
Hit Identification & Virtual Screening
Active Learning Applications
- Improved diversity of top scoring ligands in Active Learning ABFEP by using 3D features extracted from Glide poses in ML model building
- Researchers can now specify different batch sizes and selection rules to exploit or explore for each iteration in Active Learning simulations
Lead Optimization
Protein FEP
- View trajectories and structural output from FEP+ Residue Scans in the FEP+ interface
- Rationalize key interactions in ligand binding using per-contact residue interaction energy analysis which is new for ABFEP
- Easily identify disconnected sub-maps in a busy FEP map
Spectroscopy
- More accurate NMR spectra predictions by identifying magnetically inequivalent nuclei
Macrocycles
- Automatically enumerate and cyclize peptide sequences from FASTA files with the new cyclize_peptide.py script
- Ring template generation for Glide macrocycle docking with bespoke parameters is now automated by the macrocycle_template_gen.py script
- An updated macrocycle_sample.py script with greater control of sampling options and a new receptor-aware macrocycle sampling algorithm that includes surrounding receptor atoms to restrict conformational search space
. Updated macrocycle_sample.py script replaces macro_sample.py
- Improved handling of ring nitrogen atom substituents during ring template conformation generation
- tug_align.py now supports 2D ligand files as inputs
- tug_align.py exposes several new command-line options that allow finer control of the alignment convergence criteria which are useful in reducing convergence times for large molecules such as cyclic peptides
Medical Chemistry Design
Ligand Designer
- Enable user-specificed or automatically generated ligand protonation and tautomeric states from the 2D/3D editing workflow for MCS Docking
Biologics Drug Discovery
- Completely rewritten MMGBSA Residue Scanning backend that is more reliable and has improved support for a wider variety of non-standard amino acids and mutation of DNA/RNA
- New high-throughput, machine learning-based antibody and nanobody structure prediction with ImmuneBuilder. With throughput of about one minute per structure, it is suitable for batch modeling of thousands of structures
- Automatically identify and annotate for visualization TCR alpha and beta chains from a FASTA file (commandline run_tcr_modeling.py)
- Updated N-glycosylation PROSITE pattern that is less restrictive
Materials Science
GUI for Quantum ESPRESSO
Product: Quantum ESPRESSO (QE) Interface
- Workflow solution to calculate the defect energy
- Workflow action menu (WAM) for output from periodic DFT convergence test
- Support for setting total magnetization/charge for each structure
- Support for computing thermodynamic properties via dynmat.x (command line)
- Support for stopping an NEB calculation and returning intermediate structures
Materials Informatics
Product: MS Informatics
- Formulation ML: Option to control advanced settings
- Machine Learning Property: Skip structures outside the model scope
- Machine Learning Property: Prediction of singlet (S0) to triplet (T1) energy
- Machine Learning Property: Prediction of hole / electron reorganization energy
- Machine Learning Property: Prediction of orbital (HOMO / LUMO) energy
- Machine Learning Property: Updates to existing models
Coarse-Grained (CG) Molecular Dynamics
Product: MS CG
- Automated CG Mapping: Mapping MARTINI for speciality chemicals / polymers
- CG FF Builder: Support for exporting atomistic reference data
Dielectric properties
Product: MS Dielectric
- Complex Permittivity: Linear fitting parameter retained during exponential fitting
Reactivity
Product: MS Reactivity
- Nanoreactor: Control over thermostat bath temperature
- Nanoreactor: Support for parallelization of xTB dynamics simulations
- Reaction Workflow: Support for the use of the xTB Hessian for transition states
- Reaction Workflow: Use of input conformers when conformation search fails
- Reaction Workflow: Improved SCF convergence for energy calculations
Microkinetics
Product: MS Microkinetics
- Microkinetic Modeling: Improved speed/scalability by up to 2 orders of magnitude
- Microkinetic Modeling: Improved model for multiple catalysts / catalyst site types
- Microkinetic Modeling: Improved data visualization in the viewer
- Microkinetic Modeling: Job name shown in the viewer
Reactive Interface Simulator
Product: MS RIS
- Solid Electrolyte Interphase: Improved subjob queuing coordination
- Solid Electrolyte Interphase: Support for constant pressure (NpT) simulations (command-line)
MS Maestro Builders and Tools
- GUI panel to digitally design, manage, and visualize OLED devices
- Single Complex: Improved UI for better usability
- Solvate System: Support for generating multiple configurations by random seeds
Classical Mechanics
- Workflow solution to compute thin plane shear friction
- Barrier Potential for MD: Support for reading barrier information from entry
- Evaporation: Option to Description total number of molecules removed from the system
- Evaporation: Information tied to barriers (when applied) logged in the output
- Polymer Crosslink: Improved speed by efficient checking for ring spears
- Trajectory Density Analysis: Option to display multiple density depths
- Trajectory Density Analysis: Export option for 2D heat-map Description
Quantum Mechanics
- Workflow solution to Description phase diagrams based on energy
- Workflow solution to compute and analyze computational ellipsometry data
- QM Convergence Monitor: Easy access to the structure from the last step
Education Content
Life Science
- New tutorial: Refining crystallographic protein-ligand structures using GlideXtal and Phenix/OPLS
Materials Science
- New tutorial: Automated Martini Fitting for Coarse-Grained Simulations
- New tutorial: Thin Shear
- New tutorial: Defect Energy Calculation
- New tutorial: Optoelectronics Device Designer
- New tutorial: Computational Ellipsometry
- New tutorial: Phase Diagrams
- New tutorial: Ab initio Molecular Dynamics Simulations of Li-ion Diffusion in Solid State Electrolytes
- Updated tutorial: Microkinetic Modeling
- Updated tutorial: Organometallic Complexes
LiveDesign
What's upcoming in 2025-1
- Extended support for biologics drug discovery: Synchronous selection between Sequence Viewer and 3D Visualizer, support for biologic entities in models which expect atomistic representation, and enhancements for handling non-canonical monomers throughout the application
- Data import performance improvements: Faster small molecule file import and large enumeration result import
- Enhanced formula capabilities: Support multiple value inputs to a formula and align multiple value outputs from a formula by experiment, lot, or pose

Schrödinger Softwareprovide accurate, reliable, and high performance computational technology to solve real-world problems in life science research. It can be used to build, edit, run and analyse molecules. The Schrödinger-Suite of applications have a graphical user interface called Maestro. Using the Maestro you can prepare your structure for refinement. The following products are available: CombiClide, ConfGen, Core Hopping, Desmond, Epik, Glide, Glide, Impact, Jaguar ( high-performance ab initio package), Liaison, LigPrep, MacroModel, MCPRO+, Phase, Prime, PrimeX, QikProp, QSite, Semi-Empirical, SiteMap, and Strike.
Schrödinger Release - New Features 2025-1
Schrödinger, LLCprovides scientific software solutions and services for life sciences and materials research, as well as academic, government, and non-profit institutions around the world. It offers small-molecule drug discovery, biologics, materials science, and discovery informatics solutions; and PyMOL, a 3D molecular visualization solution. The company was founded in 1990 and is based in Portland, Oregon with operations in the United States, Europe, Japan, and India.

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Free Download Schrodinger Suites 2025-1 | 7.8 Gb
The software developerSchrödingercontinuously strive to develop scientific solutions that push the boundaries of molecular design and are delighted to share enhanced drug discovery and materials workflows inSchrödinger's 2025-1software release
Owner:Schrödinger, LLC
Product Name:Schrödinger Suites
Version:2025-1 Commercial Version
Supported Architectures:x64
Website Home Page :[Ссылки доступны только зарегистрированным пользователям . Регистрируйся тут...]
Languages Supported:english
System Requirements:Windows *
Size:7.8 Gb.


Small Molecule Drug Discovery
Target Validation & Structure Enablement
Protein Preparation
- Improved peptide bond connectivity by better integration of sequence information in the Protein Preparation Workflow (PPW)
Protein X-Ray Refinement
- Phenix/OPLS can now run from CIF files containing reflections
Cryo-EM Model Refinement
- Improved support of macrocycles in GlideEM/GlideXtal
Binding Site & Structure Analysis
Binding Site Characterization
- Rationalize kinase selectivity challenges using the Kinase Conservation Analysis Interface that combines sequence and complex structural information: Identify promising selectivity handle residues to modulate ligand kinase selectivity that can be tested with FEP+ Residue Scan
Desmond Molecular Dynamics
- Optimize the unbinding kinetics of protein-ligand complexes using dissolution rate predictions based on unbinding pathways identified by enhanced sampling methods
Mixed Solvent MD (MxMD)
- Identify potential binding sites and assess drugability of competitive and allosteric binding sites with the full release of a Mixed Solvent Molecular Dynamics Interface to setup and analyze MxMD simulations
Hit Identification & Virtual Screening
Active Learning Applications
- Improved diversity of top scoring ligands in Active Learning ABFEP by using 3D features extracted from Glide poses in ML model building
- Researchers can now specify different batch sizes and selection rules to exploit or explore for each iteration in Active Learning simulations
Lead Optimization
Protein FEP
- View trajectories and structural output from FEP+ Residue Scans in the FEP+ interface
- Rationalize key interactions in ligand binding using per-contact residue interaction energy analysis which is new for ABFEP
- Easily identify disconnected sub-maps in a busy FEP map
Spectroscopy
- More accurate NMR spectra predictions by identifying magnetically inequivalent nuclei
Macrocycles
- Automatically enumerate and cyclize peptide sequences from FASTA files with the new cyclize_peptide.py script
- Ring template generation for Glide macrocycle docking with bespoke parameters is now automated by the macrocycle_template_gen.py script
- An updated macrocycle_sample.py script with greater control of sampling options and a new receptor-aware macrocycle sampling algorithm that includes surrounding receptor atoms to restrict conformational search space
. Updated macrocycle_sample.py script replaces macro_sample.py
- Improved handling of ring nitrogen atom substituents during ring template conformation generation
- tug_align.py now supports 2D ligand files as inputs
- tug_align.py exposes several new command-line options that allow finer control of the alignment convergence criteria which are useful in reducing convergence times for large molecules such as cyclic peptides
Medical Chemistry Design
Ligand Designer
- Enable user-specificed or automatically generated ligand protonation and tautomeric states from the 2D/3D editing workflow for MCS Docking
Biologics Drug Discovery
- Completely rewritten MMGBSA Residue Scanning backend that is more reliable and has improved support for a wider variety of non-standard amino acids and mutation of DNA/RNA
- New high-throughput, machine learning-based antibody and nanobody structure prediction with ImmuneBuilder. With throughput of about one minute per structure, it is suitable for batch modeling of thousands of structures
- Automatically identify and annotate for visualization TCR alpha and beta chains from a FASTA file (commandline run_tcr_modeling.py)
- Updated N-glycosylation PROSITE pattern that is less restrictive
Materials Science
GUI for Quantum ESPRESSO
Product: Quantum ESPRESSO (QE) Interface
- Workflow solution to calculate the defect energy
- Workflow action menu (WAM) for output from periodic DFT convergence test
- Support for setting total magnetization/charge for each structure
- Support for computing thermodynamic properties via dynmat.x (command line)
- Support for stopping an NEB calculation and returning intermediate structures
Materials Informatics
Product: MS Informatics
- Formulation ML: Option to control advanced settings
- Machine Learning Property: Skip structures outside the model scope
- Machine Learning Property: Prediction of singlet (S0) to triplet (T1) energy
- Machine Learning Property: Prediction of hole / electron reorganization energy
- Machine Learning Property: Prediction of orbital (HOMO / LUMO) energy
- Machine Learning Property: Updates to existing models
Coarse-Grained (CG) Molecular Dynamics
Product: MS CG
- Automated CG Mapping: Mapping MARTINI for speciality chemicals / polymers
- CG FF Builder: Support for exporting atomistic reference data
Dielectric properties
Product: MS Dielectric
- Complex Permittivity: Linear fitting parameter retained during exponential fitting
Reactivity
Product: MS Reactivity
- Nanoreactor: Control over thermostat bath temperature
- Nanoreactor: Support for parallelization of xTB dynamics simulations
- Reaction Workflow: Support for the use of the xTB Hessian for transition states
- Reaction Workflow: Use of input conformers when conformation search fails
- Reaction Workflow: Improved SCF convergence for energy calculations
Microkinetics
Product: MS Microkinetics
- Microkinetic Modeling: Improved speed/scalability by up to 2 orders of magnitude
- Microkinetic Modeling: Improved model for multiple catalysts / catalyst site types
- Microkinetic Modeling: Improved data visualization in the viewer
- Microkinetic Modeling: Job name shown in the viewer
Reactive Interface Simulator
Product: MS RIS
- Solid Electrolyte Interphase: Improved subjob queuing coordination
- Solid Electrolyte Interphase: Support for constant pressure (NpT) simulations (command-line)
MS Maestro Builders and Tools
- GUI panel to digitally design, manage, and visualize OLED devices
- Single Complex: Improved UI for better usability
- Solvate System: Support for generating multiple configurations by random seeds
Classical Mechanics
- Workflow solution to compute thin plane shear friction
- Barrier Potential for MD: Support for reading barrier information from entry
- Evaporation: Option to Description total number of molecules removed from the system
- Evaporation: Information tied to barriers (when applied) logged in the output
- Polymer Crosslink: Improved speed by efficient checking for ring spears
- Trajectory Density Analysis: Option to display multiple density depths
- Trajectory Density Analysis: Export option for 2D heat-map Description
Quantum Mechanics
- Workflow solution to Description phase diagrams based on energy
- Workflow solution to compute and analyze computational ellipsometry data
- QM Convergence Monitor: Easy access to the structure from the last step
Education Content
Life Science
- New tutorial: Refining crystallographic protein-ligand structures using GlideXtal and Phenix/OPLS
Materials Science
- New tutorial: Automated Martini Fitting for Coarse-Grained Simulations
- New tutorial: Thin Shear
- New tutorial: Defect Energy Calculation
- New tutorial: Optoelectronics Device Designer
- New tutorial: Computational Ellipsometry
- New tutorial: Phase Diagrams
- New tutorial: Ab initio Molecular Dynamics Simulations of Li-ion Diffusion in Solid State Electrolytes
- Updated tutorial: Microkinetic Modeling
- Updated tutorial: Organometallic Complexes
LiveDesign
What's upcoming in 2025-1
- Extended support for biologics drug discovery: Synchronous selection between Sequence Viewer and 3D Visualizer, support for biologic entities in models which expect atomistic representation, and enhancements for handling non-canonical monomers throughout the application
- Data import performance improvements: Faster small molecule file import and large enumeration result import
- Enhanced formula capabilities: Support multiple value inputs to a formula and align multiple value outputs from a formula by experiment, lot, or pose

Schrödinger Softwareprovide accurate, reliable, and high performance computational technology to solve real-world problems in life science research. It can be used to build, edit, run and analyse molecules. The Schrödinger-Suite of applications have a graphical user interface called Maestro. Using the Maestro you can prepare your structure for refinement. The following products are available: CombiClide, ConfGen, Core Hopping, Desmond, Epik, Glide, Glide, Impact, Jaguar ( high-performance ab initio package), Liaison, LigPrep, MacroModel, MCPRO+, Phase, Prime, PrimeX, QikProp, QSite, Semi-Empirical, SiteMap, and Strike.
Schrödinger Release - New Features 2025-1
Schrödinger, LLCprovides scientific software solutions and services for life sciences and materials research, as well as academic, government, and non-profit institutions around the world. It offers small-molecule drug discovery, biologics, materials science, and discovery informatics solutions; and PyMOL, a 3D molecular visualization solution. The company was founded in 1990 and is based in Portland, Oregon with operations in the United States, Europe, Japan, and India.

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Sejda PDF Desktop - Pleasant and productive PDF software that you'll love to use. Full-featured to help you with your PDF tasks. Sejda PDF Desktop is free to use within daily limits. Upgrade for premium features and unlimited use.

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SmartFTP is an FTP (File Transfer Protocol), FTPS, SFTP, WebDAV, Amazon S3, Backblaze B2, Google Drive, OneDrive, SSH, Terminal client. It allows you to transfer files between your local computer and a server on the Internet. With its many basic and advanced Features SmartFTP also offers secure, reliable and efficient transfers that make it a powerful tool.

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Windows Server 2008, 2012
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Introducing StartAllBack: Windows 11 from better timeline, Embrace, enhance, unsweep classic UI from under the rug.

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https://www.startallback.com/

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Free Download Swift E Logbook 2.0.5 | 26.1 Mb
Swift-E-Logbook is the quick, easy and accurate software solution for pilots to ease the chore of logging personal flight times, and produce a record of flying experience in a EASA/JAA logbook format, complying with JAR 1.080.

Save time, no more adding up times- line by line, column by column, page by page. Digitise your trusty paper flight logbook to see your pilot logbook data in ways you've never imagined. Electronic backups or paper printouts similar to the traditional paper flight logbooks can be made, having several copies is useful in the case of loss or theft of a pilot logbook.
Logbook Features:
Automatic day / night - flight time calculations
Smart auto-fill for quick and accurate flight data entry
Integrated database of over 30,000 worldwide airfields, enter airfields flown to or from by ICAO, IATA or FAA codes
EASA/JAR-FCL compliant printouts
Runs on Windows XP, Vista, 7
Both 32 bit and 64 bit versions available
Licensed per user - user can install this software program on multiple PCs or Laptops
Record flight duty times, CAP371 FDP checker
Powerful search functions
Sunrise and sunset time calculator
Both Decimal and HH:MM time formats may be used
Keep track of expiry dates
Use multiple logbooks
Free 'Mobile Log Book' - Pocket PC companion program
Operating System:Windows XP, Vista, 7, 8/8.1, 10, 11
Home Page -[Ссылки доступны только зарегистрированным пользователям . Регистрируйся тут...]

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Free Download Systweak Photos Recovery 3.2.0.191 (x64) Multilingual Portable Fast Links | 16.1 Mb
Recover lost photos swiftly. Photos Recovery is the best software to retrieve digital images that are deleted, lost, or formatted from USB Flash Drive, memory cards, hard drive etc. Not only this but Photos Recovery can also retrieve deleted photos from different file system like FAT, FAT 32, NTFS etc.

Why choose Photos Recovery?
Photos Recovery offers a state-of-art solution to retrieve digital photos from almost any storage device.
Recover Deleted Photos
This image recovery tool lets you recover different image file stored on any storage media.
Comprehensive Scanning
Photos Recovery has a Deep Scan mode that scrubs hard drive to find buried deleted photos.
Enhanced User Interface
Photos Recovery is user friendly and is equipped with various customizable options to recover images.
How does it work?
Getting started with Photos Recovery is easy. It recovers lost images in 3 steps.
Select location
Select the target storage location from where you want to retrieve deleted photos.
Start Scan
Select the scan type. Choose Quick Scan for fast scanning and Deep for thorough.
Recover Photos
Preview scan results to recover all needed deleted digital images.
Scan Types
Photos Recovery offers two distinctive scan modes to search for lost photos. Choose either Quick Scan or Deep Scan depending on how your photos were deleted from your computer.
Quick Scan
As the name suggests, Quick Scan looks for recoverable photos that were permanently deleted using Shift+Delete. It is the quicker of the two available scan modes.
Deep Scan
Use this option to recover photos that have been lost due to your drive being formatted. It performs a systematic sector-wise scan, and thus takes more time.
Home Page-

https://www.systweak.com/photos-recovery

Rapidgator
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Free Download Systweak Photos Recovery 3.2.0.191 Multilingual Fast Links | 21.8 Mb
Recover lost photos swiftly. Photos Recovery is the best software to retrieve digital images that are deleted, lost, or formatted from USB Flash Drive, memory cards, hard drive etc. Not only this but Photos Recovery can also retrieve deleted photos from different file system like FAT, FAT 32, NTFS etc.

Why choose Photos Recovery?
Photos Recovery offers a state-of-art solution to retrieve digital photos from almost any storage device.
Recover Deleted Photos
This image recovery tool lets you recover different image file stored on any storage media.
Comprehensive Scanning
Photos Recovery has a Deep Scan mode that scrubs hard drive to find buried deleted photos.
Enhanced User Interface
Photos Recovery is user friendly and is equipped with various customizable options to recover images.
How does it work?
Getting started with Photos Recovery is easy. It recovers lost images in 3 steps.
Select location
Select the target storage location from where you want to retrieve deleted photos.
Start Scan
Select the scan type. Choose Quick Scan for fast scanning and Deep for thorough.
Recover Photos
Preview scan results to recover all needed deleted digital images.
Scan Types
Photos Recovery offers two distinctive scan modes to search for lost photos. Choose either Quick Scan or Deep Scan depending on how your photos were deleted from your computer.
Quick Scan
As the name suggests, Quick Scan looks for recoverable photos that were permanently deleted using Shift+Delete. It is the quicker of the two available scan modes.
Deep Scan
Use this option to recover photos that have been lost due to your drive being formatted. It performs a systematic sector-wise scan, and thus takes more time.
Home Page-

https://www.systweak.com/photos-recovery

Rapidgator
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Free Download ThreadNinja 1.3.8 | 131.7 Mb
What makes ThreadNinja so special? Auto-follow. Mass follow targeted Threads users, from any location in Threads (search results, your feed, another user's followers, post comments, and many more!)

Auto-unfollow
Mass unfollow users with various settings, such as only those who don't follow you back or only users followed more than X days ago.
Auto-like
Mass like thousands of other finely targeted and filtered posts on Threads with the click of a button. Auto-like your own feed, monitor a tag, or posts from anywhere in Threads.
Auto-comment
Automatically leave comments from a preset list (spintax allowed) or automatically generate context-sensitive comments using AI!
Superlike feature
Target users and like their recent posts (you can specify how many). Extremely effective method to gain more followers. Much more effective than just liking a single post!
Auto-repost
Automatically repost existing posts from a tag or keyword search, or monitor a feed.
iconTargeting filters
Filter users by number of followers, followings, posts, bio keywords, businesses, verified accounts and more. Filter pictures by number of likes, age and keywords.
Monitoring
Monitor a tag or keyword search and automatically like new pictures or follow users immediately. This ensures you are targeting only active users!
Multiple accounts
Perform all these actions on one account, or use multiple accounts simultaneously.
Track usage and growth
All usage data is tracked and charted. See which of your stategies are the most effective over time.
Targeting options
Target another user's followers or follows, tag search, users who liked or commented on a particular post, a specified location, your feed and users found on a Google search,
Account protection
Use a random time delay setting as well as "breaks" at intervals to stay under the radar and avoid getting flagged for spamming.
Import/Export ID's
Have a third-party list of users you want to follow? No problem! You can also export the usernames or post IDs to a text file to process elsewhere.
Image resizer
ThreadNinja includes a general purpose image resizer. Resize any image(s) to custom dimensions for posting on Instagram/Threads or anywhere else!
Blacklist/whitelist
Avoid unfollowing your own known friends, or following, commenting, etc. certain people you would like to avoid.
Proxy support
Although not strictly necessary, you can hide your IP if you feel the need. Private proxies are also supported.
Home Page-

https://ninjapinner.com/threadninja-threads-bot/

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Free Download TominLab WonderPen 2.5.10.7668 | 182.9 Mb
WonderPen is a writing app for both professional and amateur writers.

Features
- Tree view, drag-and-drop to reorder.
- An easy-to-use text editor that supports Markdown.
- Supports full-screen mode, lets you focus on writing.
- Docs can be exported as Image, PDF, Word, HTML, etc.
- Support whiteboard mode, in which you can add any note, table, kanban and other information.
- Auto save while editing. You can backup all docs as a single file and restore from it later.
- Add memo for each doc.
- Focus on one node of the doc tree.
- Search in all docs.
- Darkmode support.
- Data can be backed up automatically, and import and export are supported.
OS:Windows 10/11 is recommended
Home Page-

https://www.tominlab.com/en/wonderpen

Rapidgator
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Free Download Topaz Photo AI 3.5.0 macOS | 1.16 GB
Sharpen, remove noise, and increase the resolution of your photos with tomorrow's technology. Topaz Photo AI supercharges your image quality so you can focus on the creative part of photography.

Focus on your creativity rather than your tools.
AI is good at some things but bad at others. It can write sentences but can't tell a story, and it can recommend songs but can't compose music. But most importantly for us: AI is exceptionally good at improving image quality, but bad at knowing what to do with it.
We believe that stunning photography comes from artistic vision paired with world-class tools. AI will never replicate human creativity, so it's still your job to provide the vision. But just like a sharper lens or better camera, Topaz Photo AI empowers you to create images that just aren't possible with yesterday's tools.
Your photos at their very sharpest.
You won't always be able to retake a shot when your subject is blurry. Sometimes you won't even know until you're reviewing your photos on your computer.
In these cases, use Topaz Photo AI to make sure your photos are as sharp as possible. Instead of artificially boosting edge contrast like traditional sharpening, the Sharpen AI module naturally reverses the root causes of blurring (camera shake, motion blur, incorrect focus) to create more natural-looking results.
Without blurring, the sharpness remains: crisp, clear detail, free from edge halos or other artifacts.
Get sharp and clear images without noise.
It's a magical feeling to see noise evaporate while sharp detail remains.
After learning from millions of images, Topaz Photo AI's Remove Noise module can effectively understand the content of your image. It can accurately determine the difference between real image detail and noise with an astonishing level of accuracy.
Not all of your images will be noisy. For those who are, Topaz Photo AI will give you the best possible results that modern technology is capable of.
Home Page -

https://topazlabs.com/

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Free Download TweakNow WinSecret Plus 6.1.7 | 21.9 Mb
TweakNow WinSecret for Windows 10 and 11 allows users to explore the hidden settings in Windows.

This app is specifically geared for Windows, grouping numerous registry settings and delivering them from an easy and safe user interface.
With TweakNow WinSecret for Windows, you can move the Windows taskbar to the top and change the taskbar size by editing the registry value. With any app modifying the registry, it is strongly advised to have a backup to restore from in the advent of an issue.
TweakNow WinSecret for Windows makes the process easier than directly doing it via Regedit, potentially creating critical problems for a novice user. TweakNow WinSecret for Windows gives you a smooth platform to perform these tweaks in a more controlled environment.
TweakNow WinSecret for Windows is a solid option for those that want to improve their overall experience while on Windows through a simple and easy-to-navigate app.
Plus Features
Auto Dark
Automatically change app and system theme mode to light or dark
Auto Wallpaper Changer
Updates your background every day or hour with beautiful images from Bing homepage
Folder Size Analyzer
Figure out which files or folders who taking up your hard drive space
Find Duplicate
Find and remove duplicate files
Process Manager
View detail information about all running processes and change priority level for specified process
Secure Delete
Completely and securely delete sensitive file from your hard drive
Smart Shortcut
Automatically specified priority level for your favourite apps
System Information
Show detail information about your system
Track Cleaner
Protect your privacy by eliminating traces of your digital activities
Transparent Taskbar
Make your Windows Taskbar completely transparent
Troubleshooter
Fix problem with Internet connection, icon, thumbnail, and Microsoft Store
Windows Secret
Safely and easily explore Windows hidden settings
Operating System:Windows 10/11
Home Page-

https://www.tweaknow.com/

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Free Download VovSoft AI Requester 3.2 | 4.2 Mb
Vovsoft AI Requester is a program that can connect to OpenAI API with ease. The software provides a reliable and easy-to-use interface that seamlessly integrates with the latest AI technologies, including GPT-3.5, GPT-4 and DALL-E.

Chat with Artificial Intelligence
The software is designed to be user-friendly and intuitive, allowing even non-technical users to easily connect to OpenAI API and start chatting right away. Just like ChatGPT, you can connect to the OpenAI platform and start chatting with powerful AI bots that are capable of providing intelligent responses to a wide range of queries and questions.
Additionally, you can easily set the behavior of the assistant using the dedicated checkbox under the "Send" button. For example, enter prompt "You are Elon Musk". From now on, all your questions will be answered as if the artificial intelligence is Elon Musk.
Text-to-Image Generation
You can input textual descriptions or prompts and generate corresponding high-quality images. The software leverages the state-of-the-art image synthesis capabilities of DALL-E, allowing you to bring your ideas to life with stunning visuals. The software supports 1024x1024, 512x512, and 256x256 images in PNG format.
Create Image: Creates an image given a text prompt.
Create Image Variations: Creates a variation of a given image.
Edit Image: Creates an edited or extended image given an original image and a prompt. The original image must be a PNG file with transparency channel.
Operating System:Windows 11, Windows 10, Windows 8/8.1, Windows 7 (32-bit & 64-bit)
Home Page-

https://vovsoft.com/software/ai-requester/

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Free Download Watchdog Anti-Malware Premium / Business 4.3.180 Multilingual Fast Links | 26.6 Mb
Our highly acclaimed multi-engine anti-malware software helps keep your computer secure. Advanced Malware Detection and Removal, Browser Hijacker Removal, Effective Rootkit and Bootkit Detection and Removal, Real Time Protection, Anti Ransomware Protection Modules.

Real Time Protection
Watchdog Anti-Malware uses our Cloud Scanning Platform, a highly optimized cluster of servers running several anti-virus engines with the latest updates. This provides you with the power of multi-engine scanning any downsides such as drains on system resources or conflicts between programs.
Multi-Engine Malware Scanner
It's simply not practical to install dozens of different anti-virus programs on your computer because they'll conflict with each other and slow your system down, but even if you could it would be prohibitively expensive. We've come up with a way to provide you with several anti-virus scanners to catch malware that your primary anti-virus program misses - all at a fraction of the price. And it is point-and-click easy to use. Watchdog Anti-Malware is designed to neutralize viruses, trojans, rootkits, worms, spyware and adware.
Operating System:Windows 8, 8.1, 10 or 11
Home Page-

https://watchdog.dev/solutions/anti-malware/

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