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FOXO Transcription Factors
English | 2025 | ISBN: 1071642162 | 201 Pages | PDF (True) | 14 MB
This second edition volume expands on the previous edition with updates on the latest techniques and technologies used in FOXO research. The chapters in this book are organized into five parts. Part One covers biochemical techniques used to analyze phosphorylation status of FOXO proteins, identify FOXO binding partners, and assess FOXO-specific transcriptional activity. Part Two highlights genetic techniques that are used to identify functional domains and validate disease relevance. Part Three talks about biophysical and bioinformatic methods to study the structure and dynamics of FOXO proteins, and protein-protein interactions. Part Four discusses different fluorescence and imaging techniques to measure FOXO translocation, and Part Five focuses on functional studies in model organisms to characterize cell death regulation and life- and healthspan. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Framing Intellectual and Lived Spaces in Early South Asia: Sources and Boundaries
by Lucas den Boer, Elizabeth A. Cecil
English | 2020 | ISBN: 3110553163 | 269 Pages | PDF | 7.95 MB

The contributions to this book address a series of 'confrontations'―debates between intellectual communities, the interplay of texts and images, and the intersection of monumental architecture and physical terrain―and explore the ways in which the legacy of these encounters, and the human responses to them, conditioned cultural production in early South Asia (c. 4th-7th centuries CE). Rather than an agonistic term, the book uses 'confrontation' as a heuristic to examine historical moments within this pivotal period in which individuals and communities were confronted with new ideas and material expressions.
The first half of the volume addresses the intersections of textual, material, and visual forms of cultural production by focusing on three primary modes of confrontation: the relation of inscribed texts to material media, the visual articulation of literary images and, finally, the literary interpretation and reception of built landscapes. The second part of the volume focuses on confrontations both within and between intellectual communities. The articles address the dynamics between peripheral and dominant movements in the history of Indian philosophy.

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From Click to Boom: The Political Economy of E-Commerce in China (Princeton Studies in Contemporary China) by Lizhi Liu
English | November 12th, 2024 | ISBN: 0691254109 | 328 pages | True EPUB | 9.66 MB
How the world's largest e-commerce market highlights a digital path to development

How do states build vital institutions for market development? Too often, governments confront technical or political barriers to providing the rule of law, contract enforcement, and loan access. In From Click to Boom, Lizhi Liu examines a digital solution: governments strategically outsourcing tasks of institutional development and enforcement to digital platforms-a process she calls "institutional outsourcing."
China's e-commerce boom showcases this digital path to development. In merely two decades, China built from scratch a two-trillion-dollar e-commerce market, with 800 million users, seventy million jobs, and nearly fifty percent of global online retail sales. Contrary to conventional wisdom, Liu argues, this market boom occurred because of weak government institutions, not despite them. Gaps in government institutions compelled e-commerce platforms to build powerful private institutions for contract enforcement, fraud detection, and dispute resolution. For a surprisingly long period, the authoritarian government acquiesced, endorsed, and even partnered with this private institutional building despite its disruptive nature. Drawing on a plethora of interviews, original surveys, proprietary data, and a field experiment, Liu shows that the resulting e-commerce boom had far-reaching effects on China.
Institutional outsourcing nonetheless harbors its own challenges. With inadequate regulation, platforms may abuse market power, while excessive regulation stifles institutional innovation. China's regulatory oscillations toward platforms-from laissez-faire to crackdown and back to support-underscore the struggle to strike the right balance.

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Full Stack JavaScript Strategies
by Milecia McGregor
English | January 9, 2025 | ISBN: 1098122216 | 480 Pages | epub | 22,04 MB

As a working software developer, you know how to complete your tasks with solid code, whether it's on the frontend or backend. Now you're ready to move to the next level in your career, and you need to understand the subtle yet deep skills it takes to become a senior developer. This practical book shows you everything it takes to create a full-stack web application hosted on a cloud platform.
Senior staff engineer Milecia McGregor helps you see how the whole system works and how senior developers arrive at technical decisions. You'll learn about design and development principles and when to apply them. You'll also discover strategies for working with different teams and understand how the product team makes its decisions.
In four parts, this book shows you how to:
Translate designs into tasks and learn the questions you'll need to ask the product team
Walk through development considerations for the backend like overall architecture, security, and third-party services
Build the project's user interface as well as state and data management, performance, and other concerns associated with frontend apps
Connect the frontend, backend, and other systems and deploy a full stack app to production
eBook Details:
Milecia McGregor
Release Date: January 9, 2025
ISBN-13: 9781098122218
ISBN-10: 1098122216
Language: English
Format: epub
✅File Size: 22,04 MB

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Fundamental Python Programming for GUI Development with Tkinter: A Complete Beginner's Guide to Building User-Friendly Interfaces with Python's Tkinter by HILARY STANLEY
English | September 18, 2024 | ISBN: N/A | ASIN: B0D4NPF7CP | 128 pages | EPUB | 0.51 Mb
Mastering Tkinter: Your Comprehensive Guide to GUI Development in Python

Unleash the Power of Python's Standard GUI Toolkit
In the realm of Python programming, Tkinter stands as a versatile and indispensable tool for crafting intuitive and visually appealing graphical user interfaces (GUIs). This comprehensive guide serves as your definitive roadmap to mastering Tkinter, equipping you with the knowledge and skills to create exceptional desktop applications.
A Journey Through Tkinter's Landscape
From the foundational principles of widget creation and layout management to the intricacies of event handling and data binding, this book delves into every facet of Tkinter. Through clear explanations, practical examples, and step-by-step guidance, you'll gain a deep understanding of how to harness Tkinter's capabilities to build robust and user-friendly interfaces.
Key Features of This Comprehensive Guide:
* A Solid Foundation: Explore the fundamental concepts of Tkinter, including widgets, geometry managers, and event handling.
* Practical Applications: Discover how to apply Tkinter to create a wide range of GUI applications, from simple tools to complex software.
* In-Depth Exploration: Delve into advanced topics such as data visualization, game development, and cross-platform compatibility.
* Real-World Examples: Learn through practical examples that demonstrate Tkinter's versatility and power.
* Best Practices: Gain insights into best practices for GUI design, performance optimization, and accessibility.
Elevate Your Python Programming Skills
By mastering Tkinter, you'll equip yourself with a valuable skillset that opens doors to exciting career opportunities and personal projects. This book is your gateway to unlocking the full potential of Python's GUI development capabilities.
Invest in Your Future
Whether you're a seasoned Python developer or just starting your journey, this comprehensive guide will provide you with the knowledge and tools you need to excel in GUI development. Don't miss this opportunity to elevate your skills and create exceptional applications.

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Barrington Barber, "Fundamentals of Figure Drawing: A Complete Course for Artists of All Abilities"
English | ISBN: 1841934003 | 2010 | 208 pages | EPUB | 11 MB
Fully illustrated on each page to help illuminate the point being made, Barrington's sketches and drawings inspire the reader to strive to reach the same level of excellence in draughtsmanship and technical know-how. He explains how to make the most of life classes and how to handle different scenes.

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Futures of the Study of Culture: Interdisciplinary Perspectives, Global Challenges
by Doris Bachmann-Medick, Jens Kugele
English | 2020 | ISBN: 3110655098 | 320 Pages | PDF | 1.61 MB

How can we approach possible but unknown futures of the study of culture? This volume explores this question in the context of a changing global world.
The contributions in this volume discuss the necessity of significant shifts in our conceptual and epistemological frameworks. Taking into account changing institutional research settings, the authors develop pathways to future cultural research, addressing the crucial concerns of the cultural and social worlds themselves. The contributions thereby utilize contact zones within a wide range of disciplines such as cultural anthropology, sociology, cultural history, literary studies, the history of science and bioethics as well as the environmental and medical humanities.
Examining emerging inter- and transdisciplinary points of reference, the volume invites scholars in the humanities and social sciences to take part in a conversation about theories, methods, and practices for the future study of culture.

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Game On, Money Gone! Not Anymore!: Master Your Finances With Fun & Facts! by T. J. Griffin
English | May 17, 2024 | ISBN: N/A | ASIN: B0D4JSMNBD | 105 pages | EPUB | 4.71 Mb
Money Mastery for Teens: Play Smart, Save Big, Succeed Early

Did you know that learning how to manage money as a teen can set you up for life? The truth is, starting early gives you an incredible advantage:
* More Confidence in Big Decisions - From buying your first car to budgeting for college, you'll have the skills to make smart choices.
* A Head Start on Building Wealth - Begin saving and investing now, and watch your money grow over time.
* Fewer Financial Regrets Later - Avoid the stress of credit card debt, bad habits, and costly mistakes.
"Game On, Money Gone? Not Anymore!" makes learning about money fun, simple, and something you'll actually enjoy.
What's packed inside this game-changing book:
* Interactive Learning: Fun trivia, quizzes, and hands-on activities that make understanding money feel like a challenge you actually want to tackle.
* Expert Tips You Can Trust: Backed by over 30 years of financial experience, this book gives you clear, practical steps to take charge of your money.
* Tools Just for You: Worksheets to personalize what you learn and apply it to your goals-whether it's saving for a new gadget, a car, or college.
* Bonus Perks: Motivational quotes and fun facts to keep you inspired as you level up your financial skills.
This isn't just a book-it's your cheat code to a smarter, more confident financial future. Whether you're saving, spending, or planning for what's next, this book gives you everything you need to succeed.

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Germany Travel Guide 2024: Journey through History, Culture, and Adventure by Joseph J. Frailey
English | July 15, 2024 | ISBN: N/A | ASIN: B0D9J6S126 | 160 pages | EPUB | 0.44 Mb
German Travel Guide 2024

Embark on an Unforgettable Journey with the Germany Travel Guide 2024!
Have you ever dreamed of wandering through the historic streets of Berlin, tasting the finest beers in Bavaria, or exploring the romantic castles along the Rhine? Do you long to experience Germany's rich cultural tapestry, vibrant festivals, and breathtaking landscapes? The German Travel Guide 2024 is your passport to all this and more, offering a comprehensive and immersive travel experience like no other.
Imagine standing in the shadow of Neuschwanstein Castle, feeling the magic of its fairy-tale turrets. Picture yourself navigating the bustling Christmas markets, the scent of mulled wine and gingerbread filling the air. Envision a leisurely bike ride through the scenic vineyards of the Rhineland, where every turn reveals a new picturesque vista.
Benefits of Having This Book:
This travel guide is meticulously crafted to provide you with everything you need for an unforgettable adventure in Germany. Whether you're a seasoned traveler or a first-time visitor, you'll find invaluable insights, practical tips, and insider knowledge to make your trip extraordinary.
Goals of the Book:
* Discover Hidden Gems: Unearth lesser-known attractions and secret spots that only locals know about.
* Navigate with Ease: Comprehensive transportation guides, including the best ways to get around by train, bus, or car.
* Savor the Flavors: Detailed sections on local cuisine, top restaurants, and must-try dishes.
* Cultural Immersion: Insights into German festivals, traditions, and the arts scene.
* Stay Comfortable: Extensive accommodation options, from luxury hotels to charming B&Bs.
Why This Guide is a Must-Have:
This guide isn't just a collection of travel tips; it's a narrative journey that will keep you engaged from start to finish. You'll feel as if you're exploring Germany with a knowledgeable friend who knows all the best places and experiences.
Spoiler Alert:
You'll discover the best times to visit Berlin's iconic landmarks, the hidden routes through Bavaria's countryside, and the top spots for wine tasting in the Rhineland. But there's so much more packed into these pages-unique itineraries, practical travel advice, and cultural insights that will make your trip truly special.
Worried about missing out on the best experiences?
Fear not! This guide is updated for 2024, ensuring you have the latest information and recommendations at your fingertips. Concerned about navigating a foreign country? We've included essential German phrases and local etiquette tips to help you blend in and feel at ease. Don't just dream about Germany-experience it! Grab your copy of the German Travel Guide 2024 today and start planning the adventure of a lifetime. Whether you're exploring solo, traveling with family, or looking for a romantic getaway, this guide is the perfect companion for your journey.
The Perfect Gift:
Looking for the perfect gift for a travel enthusiast? This guide is an ideal present for anyone with a love for exploration and a curiosity for new cultures. Give the gift of adventure and discovery with the German Travel Guide 2024.
Start your journey now. Germany awaits!

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Global One Health Index Report 2022 by Xiao-Nong Zhou, Xiaokui Guo, Xiaoxi Zhang
English | EPUB (True) | 2025 | 311 Pages | ISBN : 9819748232 | 112.1 MB

This book intends to report the new results of the Global One Health Index (GOHI). The content of this book underlines the functions and importance of developing the evaluation tool (GOHI) for global One Health practice, shows the results of GOHI score in 160 countries/territories and key findings in details, and provides different policy recommendations to UN agencies, countries, and communities to promote the wide application of the One Health approach. A pilot study was conducted in 2021, and its related publications are collected in one section of the book. The book is likely to be of interest to researchers, practitioners, policy-makers, and stakeholders in applying One Health who wish to learn about the development, results, key findings, and policy recommendations of GOHI study.

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Global One Health Index Report 2022
English | 2025 | ISBN: 9819748232 | 323 Pages | PDF (True) | 17 MB
This Open Access book intends to report the new results of the Global One Health Index (GOHI). The content of this book underlines the functions and importance of developing the evaluation tool (GOHI) for global One Health practice, shows the results of GOHI score in 160 countries/territories and key findings in details, and provides different policy recommendations to UN agencies, countries, and communities to promote the wide application of the One Health approach. A pilot study was conducted in 2021, and its related publications are collected in one section of the book. The book is likely to be of interest to researchers, practitioners, policy-makers, and stakeholders in applying One Health who wish to learn about the development, results, key findings, and policy recommendations of GOHI study.

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Michael Dudley, "Great Battles of World War II: How the Allies Defeated the Axis Powers"
English | ISBN: 1784289566 | 2017 | 240 pages | EPUB | 2 MB
The Second World War was the final global conflict of the twentieth century. It involved more combatants, and a wider range of battlefield terrain than any other conflict in history, from the frozen plains of Russia to the baking Libyan desert, and from the atolls of the Pacific to the skies over Britain. In Great Battles of World War II, Dudley has taken a fresh look at the crucial battles which decided the outcome of the Second World War, beginning with the evacuation of Dunkirk in 1940, a feat that boosted the morale of a nation during its darkest hour, and reaching a climactic end with the final bloody reckoning between the Red Army and the Third Reich amongst the ruins of Berlin.

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Edward Humphreys, "Great Canadian Battles"
English | ISBN: 1841939625 | 2009 | pages | EPUB | 2 MB
208 pages of excellent text, filled with wonderful photos and illustrations. This book covers the most important Canadian conflicts of the last four centuries. First Edition.

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smith-alex, "Growing Vegetables: A Step-By-Step Guide to Planning, Planting and Produce"
English | ISBN: 1848377525 | 2011 | 144 pages | EPUB | 5 MB
Keeping an allotment and growing one's own produce is regaining its former popularity as a productive and environmentally-friendly hobby. This title offers invaluable seasonal advice on a week-by-week basis to ensure a healthy and fruitful allotment all year round.

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Handbook of the Roman Imperial Navy: Organisation of the Roman Imperial Navy by John Richardson
English | June 6, 2024 | ISBN: 1805415492 | 122 pages | PDF | 14 Mb
This rich history of the Roman Imperial Navy and the sailors who manned their fleets deserve to be fully acknowledged. Most know that the legions of Rome fought and defended the Roman Empire but without their Imperial Navy this empire may never have been able to expand its frontier's This book well researched covers the organisation of the Imperial navy its ships plus both officer's and crews.

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