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Introduction to Organic and Medicinal Chemistry
by Keighley, Nathan
English | 2025 | ISBN: 1032851562 | 228 pages | True PDF EPUB | 27.47 MB

This text is designed to be an undergraduate reference textbook for students of chemistry who aim to select degree modules geared towards medicinal chemistry. The first two chapters offer an overview of basic organic chemistry, followed by organic synthesis in Chapter 3, with an emphasis on the importance of synthetic procedures in relation to the chemistry of drug design. In Chapter 4, the book covers foundational aspects of biochemistry and biomedical science to provide a basis for students understanding where and how drugs work on selected targets. Later, the book explains how medicines have been created for selected topics in medicinal chemistry - namely against pathogens, cancer and neurological targets.
Features:
User-friendly text that deals with key methods in organic synthesis and medicinal chemistry
An overture of drug design against disease targets
An introduction to the molecular basis of disease and key topics in medicinal chemistry
Geared toward chemistry undergraduates with an interest in pursuing medicinal chemistry further into their degree
A complete set of tutorial questions and answers for each chapter

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Investigative Electrocardiography in Epidemiological Studies and Clinical Trials By Pentti Rautaharju MD, PhD, Farida Rautaharju PhD (auth.)
2007 | 289 Pages | ISBN: 1846284651 | PDF | 2 MB
Electrocardiology is a relatively new modality in clinical trials, but electrocardiograms (ECGs) have already become established as a valuable research tool for investigation of morbidity and mortality risk associated with various clinical and subclinical conditions. ECGs have also become a crucial tool when investigating adverse cardiac events associated with administration of new drugs.Investigative Electrocardiography in Epidemiological Studies and Clinical Trials reviews the prevalence and incidence and emphasizes the prognostic implications of common ECG abnormalities in contrasting populations. It provides a comprehensive, penetrating and critical analysis of topics such as QT prolongation in clinical drug trials, left ventricular hypertrophy, myocardial ischemia/infarction and epidemiological consideration of relative risks associated with ECG abnormalities. As such it is an essential tool in epidemiological or clinical research using ECGs and in investigations of possible adverse responses of new pharmacological agents.With emphasis on providing international coverage of the topic, the well-respected authors present key information on ECG procedures, epidemiology, problem areas, mortality and morbidity risk. These topics are of particular interest to electrocardiologists, investigators in active ECG research in medical clinics participating in clinical trials, epidemiologists, cardiologists, pharmaceutical companies and regulatory bodies.

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Ireland: A Short History (Short Histories), 5th Edition by Joseph Coohill
English | 1 Aug. 2024 | ISBN: 0861543688 | True EPUB | 256 pages | 1.7 MB
From the first prehistoric inhabitants of the island to the Windsor Framework for Northern Ireland, this uniquely concise account of Ireland and its people reveals how modern Irish society is the product of a rich, multivalent history.

Combining factual information with a critical approach, Coohill covers all the key events, including the Great Famine, Home Rule, the Good Friday Agreement and Brexit. Newly revised and updated, this highly accessible and balanced account will continue to provide a valuable resource to all those wishing to acquaint themselves further with the complex history of Ireland and Irish people.

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Italy in a Wineglass: The Story of Italy Through Its Wines by Marc Millon
English | May 28, 2024 | ISBN: 1685890970 | 336 pages | PDF | 7.33 Mb
"Compulsory reading" - The International Wine Review

A leading travel writer guides readers on a sumptuous journey through time and flavor to understand how and why wine transformed Italy . . .
"It's not often that a wine writer can engross and enthrall you with the history of a culture where wine merely plays its part along with many other players. Marc Millon does this absorbingly and impressively, telling the intriguing, exasperating, but ultimately optimistic story of Italy and its wines." -OZ CLARKE, author of The History of Wine in 100 Bottles
The world is enamored with Italy: its culture, art, food, and fashion, its beautiful landscapes, and famous cities-and, of course, its wine.
From the ancient Greeks to the Medici, and from fascism to feminism, Italy has always been entwined with wine. Through the millennia, it has been a celebratory libation at great events, given solace in times of despair, and fortified warriors before battle. Whether Possessioni Rosso, still made by descendants of Dante; Barolo "Lazzarito," from a wine estate founded by the son of Italy's first king; or Terre Rosse di Giabbascio, pressed from grapes grown on ex-Mafia land, the peninsula's wines provide an intoxicating insight into the ideas, events, and personalities that shaped Italian history.
If history can sometimes be throat-achingly dry, writer and wine expert Marc Millon serves up a delightfully fresh take on Italy's past, present, and future, best enjoyed with a glass in hand.

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Java Generics and Collections, 2nd Edition (Third Early Release) by Maurice Naftalin
English | 2024 | ISBN: 9781098136666 | 300 pages | EPUB | 4.06 Mb
Java Generics and Collections has been the go-to guide to generics for more than a decade. This second edition covers Java 21, providing a clear guide to generics from their most common uses to the strangest corner cases, giving you everything you need to know to use and write generic APIs effectively. It covers the collections library thoroughly, so you'll always know how and when to use each collection for any given task. And it explains stream processing, so you'll know which model to use and how they interoperate to get the best out of the platform library.

This indispensable guide covers
Fundamentals of generics: type parameters and generic methods
Subtyping and wildcards
Generics and reflection
Design patterns for generics
Sets, queues, lists, maps, and their implementations
Concurrent programming and thread safety with collections
Performance of different collection implementations
Best practices for using and extending the Java collections framework
Design philosophy and comparison with other collections libraries

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Maria Litvin, "Java Methods: Object-Oriented Programming and Data Structures Ed 4"
English | ISBN: 0997252820 | 2021 | 528 pages | PDF | 97 MB
This is the fourth edition of the popular computer science textbook Java Methods. The book offers a thorough introduction to the concepts and practices of object-oriented programming in Java. It also introduces the most common data structures and related algorithms and their implementations in the Java collections framework. Chapters 1-14 follow the syllabus of the AP Computer Science course. They will prepare you well for the AP CS exam. Chapters 15-18 on file input and output, graphics, graphical user interfaces, and events handling in Java will give you a better sense of real-world Java programming; this material also makes case studies, labs, and exercises more fun. The book follows four main threads: Java syntax and style, OOP concepts and techniques, algorithms, and Java libraries. As in the software engineering profession itself, these threads are interwoven into an inseparable braid. Working through this book will not make you a Java expert right away, but it will bring you to the level of an entry-level Java programmer with a better than average understanding of the fundamental concepts.

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Katy Sprinkel, "JoJo Siwa: The Sweetest Dream"
English | 2019 | ISBN: 1629377201 | EPUB | pages: 112 | 9.2 mb
Jojo Siwa is simply unstoppable! Whether dancing, singing, acting, or making hilarious YouTube videos, JoJo has proven-at only 15-that she can do it all. JoJo Siwa: The Sweetest Dream has everything you need to know about this young star's rise to incredible success, from making a splash on shows like Abby's Ultimate Dance Competition and Dance Moms to releasing hit songs like "Boomerang" and "High Top Shoes" and performing all around the world. With dozens of full-color photographs, memorable quotes, and little-known facts, this is a must-have for all Siwanatorz!

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Mario Marcello Neto, "Justice League and Terrorism in Cartoons"
English | 2022 | ISBN: 6205252120 | PDF | pages: 69 | 3.1 mb
This book analyzes the representation of the superheroes in the animated film Justice League (DC Comics, 2001) regarding the anti-terrorist discourse. This cartoon has as main characters some of the most established superheroes such as: Superman, Batman, Wonder Woman, Green Lantern, among others. This animation is broadcasted in open television in Brazil, a fact that amplifies even more its diffusion in our society. Considering that this animation was broadcasted on television in the year that one of the greatest terrorist attacks occurred: the fall of the World Trade Center in 2001, we intend to make a quantitative analysis, in relation to the number of episodes with an anti-terrorist theme, and a qualitative analysis, analyzing the form of discourse, the aesthetics, and the character in which it was involved. In this way, this book conducts a case study on the before and after the so-called "9/11", using the aforementioned animation as a source of analysis.

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Kokoda Legend: Captain Sam Templeton by David Howell
English | June 5, 2024 | ISBN: 1923004980 | 296 pages | PDF | 5.40 Mb
One of the finest soldiers and most courageous leaders I have ever known. - Lt Doug McClean, D Coy, 39th Battalion

If you have trekked Kokoda, then the campsite of Templeton's Crossing will be familiar. Discover the story of the man behind the name.
Captain Sam Templeton was the first Australian officer to be captured by the Japanese in the Kokoda Campaign. After being interrogated by his captors he was executed on the battlefield.
Prior to facing his enemy, Templeton had predicted his fate, telling one of his platoon commanders, that if 'he went into action, he wouldn't come back'. Having resigned himself to his destiny, Templeton misled his captors on the numerical strength of the Australian forces waiting in Kokoda and Port Moresby.
Did the misinformation given by a militia officer slow the initial push by the Yokoyama Advance Force into the Owen Stanley Range, allowing the Australian Imperial Force to join the fight earlier? Did Templeton create doubt in the mind of the commander of the South Seas Force, influencing an operational change for the attack on Port Moresby?
A quiet and often aloof character originally from Belfast, Captain Sam Templeton is mentioned in just about every book written about Kokoda. Prior to fighting in New Guinea, Templeton is reputed to have helped quash the Irish rebellion, served in submarines with the Royal Navy during the First World War and to have fought with the International Brigade during the Spanish Civil War.
Kokoda Legend goes beyond the myth to discover the real contribution Captain Sam Templeton made to stopping the Japanese advance over the Owen Stanley Range in 1942.

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Lasers in Oral and Maxillofacial Surgery by Stefan Stübinger, Florian Klämpfl, Michael Schmidt, Hans-Florian Zeilhofer
English | EPUB (True) | 2020 | 269 Pages | ISBN : 3030296032 | 103.2 MB
This book provides surgeons with important insights into laser technologies as well as a sound understanding of their current and potential applications within oral and maxillofacial surgery and related disciplines. The opening chapters focus on the relevant physical background, the technology of the typically used lasers, laser-tissue interactions, and the treatment systems. Detailed information is then provided on the various established applications of laser treatments, including in relation to skin and mucosa and the dental hard tissues and bone. Special applications are also described, for example with respect to periodontal surgery, peri-implantitis therapy, photodynamic treatment, holography and additive manufacturing. The book closes by examining technologies that will soon be available for application in hospitals, topics which are currently the subject of research, and laser safety. Beyond surgeons, the book will be of value for engineers and scientists working in the field of medical engineering using lasers.

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J. Collins, "Leadership Learning: Knowledge into Action"
English | 2008 | pages: 240 | ISBN: 0230516106, 1349354325 | PDF | 0,8 mb
Taking it theme from the fifth annual Studying Leadership Conference held at Cranfield School of Management, Leadership Learning explores the challenge of learning and developing leadership in the 21st century.This is the second of two books to emerge from the conference, taking the theme 'Knowledge into Action'.

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Learning from Clinical Cases in Primary Care
by Samar Razaq
English | 2025 | ISBN: 1032577207 | 188 pages | True PDF EPUB | 11.33 MB

This new book is designed around 20 clinical cases, each representative of scenarios encountered by doctors who work in primary care and which will prompt learning in related issues surrounding each clinical scenario. Each case description concludes with an initial exam style question, which Membership of the Royal College of General Practitioners (MRCGP) candidates will recognize as being directed towards learning for the Applied Knowledge Test (AKT). An expanded answer to that initial question is followed by a detailed explanation, concluding with further questions for self-assessment and reflection.

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Learning Serverless Security (Second Early Release)
English | 2024 | ISBN: 9781098149000 | 400 pages | EPUB | 3.98 Mb
Despite the increased adoption of serverless computing services around the world, a big gap still exists when it comes to serverless security knowledge and expertise. This gap comes with a steep price: the increased risk of data breaches as more companies store their data in the cloud.

This practical guide covers the relevant offensive and defensive security techniques to audit and secure serverless applications running on AWS, Azure, and Google Cloud. You'll learn how to attack and defend a variety of vulnerable serverless applications using the step-by-step instructions. By the end of this book, you'll have a solid understanding on how to prevent a variety of serverless application attacks and privilege escalation techniques.
Author Joshua Arvin Lat, chief technology officer at NuWorks Interactive Labs, shows you how to
Identify and exploit vulnerabilities within modern serverless applications
Perform privilege escalation techniques in cloud environments
Use automated tools and services for offensive and defensive security
Configure authentication and identity services properly on AWS, Azure, and Google Cloud
Implement security strategies and best practices to prevent a variety of serverless application attacks
Audit serverless environments using a variety of security tools and frameworks

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Uday Chand Jha, "Legume Crop Wild Relatives: Their Role in Improving Climate Resilient Legumes"
English | ISBN: 1032562234 | 2024 | 212 pages | EPUB, PDF | 5 MB + 6 MB
Grain legume crops are an important component of global food and nutritional security and help in maintaining agro-ecological systems. They fix atmospheric nitrogen via the root-inhabiting rhizobacteria, thereby minimising the harmful effects caused by the excessive application of synthetic nitrogenous fertilizers in the soil environment. There has been less focus on legume crop wild relatives for harnessing their potential traits and novel gene(s) to incorporate them into the cultivated legumes for developing climate-resilient grain legumes. In this edited book, we will highlight the importance of various potential traits of crop wild relatives, which are yet to be properly harnessed for designing future climate-resilient grain legumes. We also update how advances in molecular genetics and genomics have enabled the underpinning of several candidate genes/genomic regions in various crop wild relatives harbouring adaptive traits that confer climate resilience in grain legumes.

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Jeff Hill, "Life Events and Rites of Passage: The Customs and Symbols of Major Life-Cycle Milestones, Including Cultural, Secular, and Religious Traditions Observed in the United States"
English | 2007 | pages: 518 | ISBN: 0780807359 | PDF | 2,2 mb
"Provides information about the history, symbols, customs, and traditions of important life-cycle events within the broad range of cultural and religious groups in the United States. Entries are arranged in sections on birth and childhood, coming of age, adulthood, and death and mourning"-Provided by ✅Publisher.

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