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Eduard Torrents, "Ribonucleotide Reductase Family: Genetics and Genomics: Genetics & Genomics"
English | ISBN: 1606924192 | 2009 | 99 pages | PDF | 6 MB
Ribonucleotide reductase (RNR), a universal enzyme present in essentially all living cells and organisms, has a central role in DNA replication and repair by catalysing production of deoxyribonucleotides from the corresponding ribonucleotides. Three major classes of RNRs are known, differing in their cofactor requirements: class I RNRs (with subclasses Ia and Ib) carry a stable tyrosyl radical and are oxygen-dependent, class II RNRs require the vitamin B12 cofactor 5'-deoxyadenosylcobalamin and are oxygen-independent, and class III RNRs carry a stable glycyl radical and are oxygen-sensitive. Despite these differences, all classes have a similar reaction mechanism and the same highly specific catalytic core structure, indicating that they evolved from a common ancestor. Biochemical studies of RNRs from selected model organisms in combination with the vast number of deduced RNR sequences from publicly available complete genomic sequences show that whereas eukaryotes and their viruses with few exceptions contain only class Ia RNRs, all three major RNR classes are found among prokaryotes and bacteriophages and quite often one organism encodes more than one class of RNR. They are compiled in an open access database, called RNRdb for Ribonucleotide Reductase database that is available athttp://rnrdb.molbio.su.se. RNRs are produced in a strictly controlled way depending upon growth phase and environmental cues. The authors describe a comprehensive summary of how the expression of RNR genes is regulated in several eubacterial organisms and in yeast. Due to RNR's importance for the realisation of DNA replication, it has been recognised as a possible target for antiproliferative therapy. The authors present a comprehensive summary of RNR-specific inhibitors that have reached clinical trials and/or are currently used in clinical therapy.

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Rick Steves England by Rick Steves
English | September 17, 2024 | ISBN: 1641716118 | 968 pages | MOBI | 48 Mb
Hike the wild moors of Dartmoor, explore the scenic bays of Cornwall, and dive into history at Hadrian's Wall: England is yours to discover with Rick Steves! Inside Rick Steves England you'll find:Comprehensive coverage for spending two weeks or more in EnglandRick's strategic advice on how to get the most out of your time and money, with rankings of his must-see favoritesTop sights and hidden gems, from the ancient and mysterious Stonehenge to cozy corner pubsHow to connect with local culture: Enjoy an evening at the theatre, take high tea in a classic hotel, or cheer on the team with fans at a football matchBeat the crowds, skip the lines, and avoid tourist traps with Rick's candid, humorous insightThe best places to eat, sleep, and relax with a pintSelf-guided walking tours of lively neighborhoods, historic sites, and museumsDetailed neighborhood and museum maps for exploring on the goUseful resources including a packing list, a phrase book of British slang, a historical overview, and recommended readingOver 900 bible-thin pages include everything worth seeing without weighing you downComplete, up-to-date information on London, Windsor and Cambridge, Canterbury, Dover, Brighton, Portsmouth, Dartmoor, Cornwall, Penzance, St. Ives, Penwith Peninsula, Bath, Glastonbury, Wells, Avebury, Stonehenge, Salisbury, Oxford, the Cotswolds, Stratford-upon-Avon, Warwick, Coventry, Ironbridge Gorge, Liverpool, Blackpool, the Lake District, Yorkshire, Durham, and moreMake the most of every day and every dollar with Rick Steves England.

Planning a shorter trip? Try Rick Steves Best of England.

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Robert Manne: A Political Memoir: Intellectual Combat in the Cold War and the Culture Wars by Robert Manne
English | December 2, 2024 | ISBN: 1760645621 | 498 pages | EPUB | 1.14 Mb
The recollections of Australia's leading public intellectual

Robert Manne is one of Australia's most profound political analysts. His memoir traces his intellectual roots, revealing how his family background and early years informed the questions he would spend his life trying to answer. It also provides a fascinating portrait of key political controversies, including intellectual combat over Pol Pot, Wilfred Burchett, Quadrant, the Stolen Generations, Manning Clark, the Howard government, the Murdoch press and much more.
During the Cold War and the culture wars, Manne clashed with some of the most influential thinkers, writers and polemicists - Noam Chomsky, Les Murray, Leonie Kramer, Tom Keneally, Isi Leibler, Helen "Demidenko" Darville, Peter Craven, Paddy McGuinness, Keith Windschuttle and Andrew Bolt. This memoir recounts with surprising and unknown detail what really happened and why.
Often subverting conventional notions of left and right, Manne is an original thinker who has helped shape the nation's discourse for decades. This is the inside story of a life of engagement and reflection, and a book for anyone interested in the shape and meaning of the past nearly fifty years of politics.

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M. Abbie, "Rock Mechanics: New Research"
English | ISBN: 1606924591 | 2009 | 324 pages | PDF | 25 MB
Rock mechanics is the theoretical and applied science of the mechanical behaviour of rock and rock masses. This book examines the hydraulic characterisation of fractured rocks, with specific reference to the fluid flow in single fractures, the interpretation of hydraulic tests, the geometrical characterisation and modelling of fracture networks.

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Sam the Trap Man: Cracking yarns and tall tales from the bush by Sam Gibson
English | December 15, 2024 | ISBN: 1991006691 | 280 pages | MOBI | 28 Mb
With cracking yarns, hilarious tales and antics to rival Barry Crump, Sam Gibson is a modern outdoorsman with an incredible life story to tell.

Sam Gibson, aka Sam the Trap Man, is a bushman through and through: hunting, fishing, trapping and adventuring - he does it all. As an unruly teenager starting to get into mischief Sam's parents and teachers struck an unusual deal, letting him take time out of school to spend it in the outdoors, a path which would first steer him away from trouble and eventually come to define his life.
In a series of cracking yarns about his life spent in the bush - which are by turns funny, thrilling, astonishing and touching - Sam tells the story of his life so far.
From shooting his first deer, to labouring through freezing cold South Island winters as a young trapper, to the time he woke up somehow covered in blood, each chapter weaves together the story of an incredible life full of adventure, hard work and a deep love for the bush and the native creatures who live in it. Protecting these animals and ecosystems is a life's calling for Sam - every decision he makes in the bush is made to help it thrive.

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Scary Halloween Recipes to Keep You Up All Night!: A Cookbook of Spooky Delights by Alicia T. White
English | February 18, 2023 | ISBN: N/A | ASIN: B0BW73TM5C | 63 pages | EPUB | 13 Mb
Scary Halloween Recipes to Keep You Up All Night!

No other holiday comes close to Halloween when it comes to partying and feasting. The recipes in this book are great for anybody who enjoys Halloween and wants to prepare some haunted beverages or snacks with a spooky twist.
The dishes in "Scary Halloween Recipes to Keep You Up All Night!" are perfect for Halloween and include things like:
* Curry Squash Soup
* Candy Corn Fudge
* Peanut Butter M&M Truffles
* Peanut Butter Cheesecake
* Pumpkin Cheesecake Bars
* Pumpkin and Peanut Butter Cup Bread
* Rainbow Skittles Fudge
* Pumpkin Mousse Pie
And even more!

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Schadenfreude, A Love Story: Me, the Germans, and 20 Years of Attempted Transformations, Unfortunate Miscommunications, and Humiliating Situations That Only They Have Words For by Rebecca Schuman
English | February 7, 2017 | ISBN: 9781250077578 | 288 pages | EPUB | 0.71 Mb
"This book is a wild and wonderful ride. Your guide, Rebecca Schuman, is a super-smart and very funny person who writes brilliantly about Germany and Germans (who are not what you think) and being young and insane and life in general and... just read it, OK?"

-Dave Barry
Sometimes Love Gets Lost in Translation
You know that feeling you get watching the elevator doors slam shut just before your toxic coworker can step in? Or seeing a parking ticket on a Hummer? There's a word for this mix of malice and joy, and the Germans (of course) invented it. It's Schadenfreude, deriving pleasure from others' misfortune. Misfortune happens to be a specialty of Slate columnist Rebecca Schuman―and this is great news for the Germans. For Rebecca adores the Vaterland with the kind of single-minded passion its Volk usually reserve for beer, soccer, and being right all the time.
Let's just say the affection isn't mutual.
Schadenfreude is the story of a teenage Jewish intellectual who falls in love - in love with a boy (who breaks her heart), a language (that's nearly impossible to master), a culture (that's nihilistic, but punctual), and a landscape (that's breathtaking when there's not a wall in the way). Rebecca is an everyday, misunderstood 90's teenager with a passion for Pearl Jam and Ethan Hawke circa Reality Bites, until two men walk into her high school Civics class: Dylan Gellner, with deep brown eyes and an even deeper soul, and Franz Kafka, hitching a ride in Dylan's backpack. These two men are the axe to the frozen sea that is Rebecca's spirit, and what flows forth is a passion for all things German. First love might be fleeting, but Kafka is forever, and in pursuit of this elusive passion Rebecca will spend two decades stuttering and stumbling through German sentences, trying to win over a people who can't be bothered.
At once a snapshot of a young woman finding herself, and a country slowly starting to stitch itself back together after nearly a century of war (both hot and cold), Schadenfreude, A Love Story is an exhilarating, hilarious, and yes, maybe even heartfelt memoir proving that sometimes the truest loves play hard to get.

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Science Pitch: Present your Research. Get to the Point
English | 2024 | ISBN: 3658448431 | 129 Pages | PDF EPUB (True) | 22 MB
How can scientists present their projects with power to the point? This book is the ultimate guide for transforming complex research into captivating, convincing Science Pitches in a given time. The innovative ESPRIT model equips scientists with tools to blend professional expertise with personal passion, ensuring every presentation resonates deeply with its target audience.

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Steven R Cartwright, Kevin L. Hughes, "Second Thessalonians: Two Early Medieval Apocalyptic Commentaries"
English | 2011 | ISBN: 1580440185 | PDF | pages: 92 | 8.3 mb
Apocalyptic speculation, in one form or another, is as persistent at the turn of this millennium as it was at the last. The commentaries of Haimo of Auxerre and Thietland of Einsiedeln offer glimpses of two links in [the] unbroken chain of the apocalyptic tradition.

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Secret Societies Of The Middle Ages: The Assassins, Templars & the Secret Tribunals of Westphalia by Thomas Keightley
English | April 1, 2005 | ISBN: 1578633346 | 428 pages | PDF | 4.59 Mb
Secret Societies of the Middle Ages explores the foundations of modern secret societies, examining the history and known facts of three very different organizations.

1. The Assassins of the Middle Easthow they evolved from an Islamic religious sect into one of the most feared groups in all the world and how the very name of this ancient order became the word used for political killings of this nature.
2. The Templars of Europefrom a pious group of protectors and dedicated crusaders to their bitter end persecuted as heretics, they introduced the concept of banking to the world while amassing a fortune of incalculable wealth.
3. The Secret Tribunals of Westphaliathe feared and selfappointed judicial group who passed judgment and performed executions in a time of lawlessness in Germany. They enjoyed popular support, providing a rudimentary and vigilante law at a time when warlords ruled and the emperor was ineffective.
The echoes of these particular societies are still heard todayfrom presidential offices to battlegrounds in the Middle East. Secret Societies of the Middle Ages, originally published in 1846, was the first book to gather information on these secret orders. This foundational reference work, upon which many contemporary histories have relied, is now back in print with an introduction by James Wasserman, author of The Templars and the Assassins: The Militia of Heaven.

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Secrets Beneath the Stone: Pyramids, Cover-Ups and the Search for Extraterrestrial Truths (Alone in the Universe)
by James Connor
English | December 12, 2024 | ASIN: B0DQ9PY9BK | 159 pages | PDF | 66 Mb

SECRETS BENEATH THE STONE FOCUSES ON THE MYSTERIES SURROUNDING THE PYRAMIDS, GOVERNMENT WORLDWIDE GOVERNMENT SILENCE AND THEIR BANS NOT ALLOWING EXCAVATION OF SEVERAL SITES. DO ANCIENT MONUMENTS HOLD THE KEYS TO OUR PAST.
JOURNEY INTO THE UNKNOWN WITH HIDDEN PYRAMIDS BURIED FOR MILLENIA. EXPLORE THE POSSIBILITY OF THE PYRAMIDS AND THEIR ALIGNMENT WITH THE CELESTIAL BODIES THE UNEXPLAINED TECHNOLOGY OUR ANCIENT ANCESTORS EXPERIENCED FIRST-HAND LEAVING MYSTERIES THAT STILL HAVE NO ANSWER TO THIS DAY.
IS HISTORY THE TRUTH AS WE HAVE BEEN TOLD OR IS THERE MORE TO OUR PLACE ON THE EARTH THAN WHAT WE ARE TOLD TO BELIEVE?
SOMEWHERE BETWEEN MYTH AND REALITY LIES THE TRUTH POSSIBLY HIDDEN IN PLAIN SIGHT.

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Andreas U. Schmidt, Giovanni Russello, Antonio Lioy, "Security and Privacy in Mobile Information and Communication Systems"
English | 2010 | pages: 187 | ISBN: 3642175015 | PDF | 2,7 mb
MobiSec 2010 was the second ICST conference on security and privacy in mobile information and communication systems. With the vast area of mobile technology research and application, the intention behind the creation of MobiSec was to make a small, but unique contribution to build a bridge between top-level research and large scale application of novel kinds of information security for mobile devices and communication.

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Seeing Around Corners: Achieving Success in Business and Life by R. Christopher Whalen, Stanley C. Middleman
English | September 17, 2024 | ISBN: N/A | ASIN: B0D5HVTN5M | 273 pages | EPUB | 2.25 Mb
Seeing Around Corners tells the inspirational rags-to-riches story of entrepreneur Stan Middleman and shares his principles for achieving business success. Follow Stan's journey from humble beginnings in Philadelphia to building Freedom Mortgage, one of the largest privately held mortgage companies in America.

Through Stan's life lessons, you'll discover how perseverance, anticipating change, and creating a shared vision for your team can help you build an enduring and successful business. Learn how Stan overcame early failures, survived the 2008 financial crisis, and led his mortgage firm to become an industry leader when competitors faltered.
Equal parts memoir, business strategy guide, and chronicle of the American dream realized, Seeing Around Corners delivers an unforgettable narrative of an entrepreneur who started from nothing and climbed his way to the top through hard work and determination. If you want to achieve great success in business and life, Stan Middleman's story will motivate, inspire, and provide actionable advice.

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Semantic Analysis and Understanding of Human Behavior in Video Streaming By Alberto Amato, Vincenzo Di Lecce, Vincenzo Piuri (auth.)
2013 | 108 Pages | ISBN: 1461454859 | PDF | 4 MB
Semantic Analysis and Understanding of Human Behaviour in Video Streaming investigates the semantic analysis of the human behaviour captured by video streaming, and introduces both theoretical and technological points of view. Video analysis based on the semantic content is in fact still an open issue for the computer vision research community, especially when real-time analysis of complex scenes is concerned.This book explores an innovative, original approach to human behaviour analysis and understanding by using the syntactical symbolic analysis of images and video streaming described by means of strings of symbols. A symbol is associated to each area of the analyzed scene. When a moving object enters an area, the corresponding symbol is appended to the string describing the motion. This approach allows for characterizing the motion of a moving object with a word composed by symbols. By studying and classifying these words we can categorize and understand the various behaviours. The main advantage of this approach lies in the simplicity of the scene and motion descriptions so that the behaviour analysis will have limited computational complexity due to the intrinsic nature both of the representations and the related operations used to manipulate them. Besides, the structure of the representations is well suited for possible parallel processing, thus allowing for speeding up the analysis when appropriate hardware architectures are used. A new methodology for design systems for hierarchical high semantic level analysis of video streaming in narrow domains is also proposed. Guidelines to design your own system are provided in this book.Designed for practitioners, computer scientists and engineers working within the fields of human computer interaction, surveillance, image processing and computer vision, this book can also be used as secondary text book for advanced-level students in computer science and engineering.

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Semantic Technology: Second Joint International Conference, JIST 2012, Nara, Japan, December 2-4, 2012. Proceedings By Cong Wang, Pascal Hitzler (auth.), Hideaki Takeda, Yuzhong Qu, Riichiro Mizoguchi, Yoshinobu Kitamura (eds.)
2013 | 390 Pages | ISBN: 3642379958 | PDF | 21 MB
This book constitutes the proceedings of the Second Joint International Semantic Technology Conference, JIST 2012, held in Nara, Japan, in December 2012. The 20 full papers and 13 short papers included in this volume were carefully reviewed and selected from 90 submissions. The regular papers deal with ontology and description logics; RDF and SPARQL; learning and discovery; semantic search; knowledge building; semantic Web application. The in-use track papers cover topics on social semantic Web and semantic search; and the special track papers have linked data in practice and database integration as a topic.

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